Glutathione is a tripeptide composed of glutamic acid, cysteine, and glycine, recognized for its multifunctional role in cosmetic formulations. It is valued for its antioxidant properties, supporting the stabilization of cosmetic products and helping to protect skin from environmental stressors. Suitable for a variety of skincare applications, Glutathione can be incorporated into formulations targeting skin tone uniformity and overall skin appearance, in compliance with global cosmetic regulations.
CAT No: 20-101-04
CAS No:70-18-8
Synonyms/Alias:glutathione;70-18-8;L-Glutathione;L-Glutathione reduced;Glutathion;Isethion;Tathion;Glutathione-SH;Glutinal;Tathione;reduced glutathione;Deltathione;Neuthion;Copren;Glutide;Triptide;Ledac;Glutatione;Glutatiol;GSH;Panaron;Glutathione SH;L-Glutatione;Glutathione (reduced);glutathione reduced;Agifutol S;L-Glutathione, reduced;L-gamma-glutamyl-L-cysteinylglycine;gamma-L-Glutamyl-L-cysteinylglycine;Glutathione [JAN];5-L-Glutamyl-L-cysteinylglycine;Glutham;gamma-L-glutamyl-L-cysteinyl-glycine;Reduced l-glutathione;CCRIS 2094;gamma-L-Glutamylcysteinylglycine;glutathione red;Aec glutathione;Glycine, L-gamma-glutamyl-L-cysteinyl-;red. glutathione;Bakezyme RX;UNII-GAN16C9B8O;(S)-2-Amino-5-(((R)-1-((carboxymethyl)amino)-3-mercapto-1-oxopropan-2-yl)amino)-5-oxopentanoic acid;EINECS 200-725-4;GAN16C9B8O;gamma-Glutamylcysteinylglycine;NSC 400639;L-Glutathione reduce;(2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid;DTXSID6023101;CHEBI:16856;N-(N-gamma-L-Glutamyl-L-cysteinyl)glycine;N-(N-L-gamma-Glutamyl-L-cysteinyl)glycine;glycine, N-(N-L-gamma-glutamyl-L-cysteinyl)-;Glutathione (Reduced type);L-glutamyl-L-cysteinylglycine;L-Glutathione (reduced form);(2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-sulfanylethyl]carbamoyl}butanoic acid;DTXCID903101;BenzenaMine, 2-[(4-Methoxyphenyl)Methoxy]-;106272-20-2;95687-20-0;GLUTATHIONE (II);GLUTATHIONE [II];MFCD00065939;GLUTATHIONE (MART.);GLUTATHIONE [MART.];GLUTATHIONE (USP-RS);GLUTATHIONE [USP-RS];[Glu(-Cys)]n-Gly;GLUTATHIONE (EP MONOGRAPH);GLUTATHIONE [EP MONOGRAPH];C10H17N3O6S;NSC400639;N5-((R)-1-((carboxymethyl)amino)-3-mercapto-1-oxopropan-2-yl)-L-glutamine;CAS-70-18-8;(S)-2-Amino-5-((R)-1-(carboxymethylamino)-3-mercapto-1-oxopropan-2-ylamino)-5-oxopentanoic acid;Glutathione, Reduced;Glutathione; l-gamma-Glutamyl-l-cysteinylglycine;SR-05000002567;Glutathione [BAN:JAN];L-gamma-glutamyl-L-cysteinyl-glycine;L-Glutathione reduced form;phytochelatins;ReadiSorb;1lbk;NSC-400639;GSH;Glu(Cys-Gly);?-L-Glutamyl-L-Cysteinyl-Glycine;5-L-Glutamyl-L-cysteinylglycine;NCGC00094976-01;gamma-Glu-Cys-Gly;Tathion (TN);Glutathione (JP18);Spectrum_000419;1oe7;1oe8;1r4w;C(N-.gamma.Glu-)G;GLUTATHIONE, L-;Glycine, L-.gamma.-glutamyl-L-cysteinyl-;GLUTATHIONE [MI];Reduced Glutathione,(S);Spectrum2_001500;Spectrum3_000946;Spectrum4_001056;Spectrum5_000940;?-Glutamylcysteinylglycine;Glutathione, Reduced Form;bmse000185;bmse000952;bmse000956;GLUTATHIONE [VANDF];Cys(N-.gamma.Glu-)-Gly;SCHEMBL9167;CHEMBL1543;GLUTATHIONE [WHO-DD];KBioGR_001352;KBioSS_000899;MLS001333069;DivK1c_000075;SPECTRUM1502248;SPBio_001519;gamma-glutamyl-cysteinyl-glycine;GTPL6737;?-L-Glutamyl-L-cysteinylglycine;L-?-glutamyl-L-cysteinylglycine;L-Glutathione reduced, 97.0%;CHEBI:60836;HMS500D17;KBio1_000075;KBio2_000899;KBio2_003467;KBio2_006035;KBio3_002012;(gamma-Glutamylcysteine)n-glycine;L-g-glutamyl-L-cysteinyl-glycine;NINDS_000075;HMS1921N22;Pharmakon1600-01502248;HARUTO HANGOVER DEFENCEPATCH;HY-D0187;L-Glutathione reduced, >=98.0%;Tox21_111371;BDBM50422268;CCG-38876;NSC758199;s4606;AKOS015999135;Tox21_111371_1;CS-7948;DB00143;FG10640;FG61468;NSC-758199;SDCCGMLS-0066687.P001;.gamma.-L-Glutamyl-L-cysteinyl-glycine;IDI1_000075;N-(N-L-?-Glutamyl-L-cysteinyl)glycine;Pharm Biol 11: 539 (1968);SMP1_000247;NCGC00264046-02;DS-14675;GSH;gamma-L-Glutamyl-L-cysteinyl-glycine;SMR000857220;SBI-0051743.P002;L-Glutathione reduced, BioXtra, >=98.0%;L-Glutathione, reduced, tested to USP spec;G0074;Glycine, N-(N-L-gamma-glutamyl-L-cysteinyl);N-(N-L-.gamma.-Glutamyl-L-cysteinyl)glycine;C00051;C02471;D00014;EN300-311690;P19615;AB00443568_03;Glutathione 100 microg/mL in Acetonitrile:Water;Q116907;SR-05000002567-1;SR-05000002567-2;BRD-K69346723-001-04-8;L-Glutathione reduced, Vetec(TM) reagent grade, >=98%;Z2183947556;Glutathione, European Pharmacopoeia (EP) Reference Standard;Glutathione, United States Pharmacopeia (USP) Reference Standard;Glutathione, Pharmaceutical Secondary Standard; Certified Reference Material;L-Glutathione reduced, cell culture tested, BioReagent, >=98.0%, powder;(2S)-2-AMINO-4-{[(1R)-1-[(CARBOXYMETHYL)CARBAMOYL]-2-SULFANYLETHYL]CARBAMOYLBUTANOIC ACID;200-725-4;glutathione; l-glutathione reduced; 5-l-glutamyl-l-cysteinylglycine; gamma-l-glutamyl-l-cysteinylglycine; gsh;
Mechanism of Action (MOA)
Glutathione, a tripeptide composed of glutamine, cysteine, and glycine, functions as a key cellular antioxidant within the skin. It participates in redox signaling pathways by modulating the balance between reactive oxygen species and cellular defense systems. Through its thiol group, glutathione supports the regeneration of other antioxidants and contributes to the maintenance of cellular homeostasis, thereby influencing processes associated with oxidative stress and overall skin vitality.
Glutathione is a versatile ingredient suitable for various cosmetic formulations.
- Incorporate into serums for daily skincare routines- Add to creams and lotions for enhanced formulation profiles- Formulate in sheet masks or leave-on treatments- Blend with other antioxidants in multi-functional products- Use in rinse-off products such as cleansers and washes- Combine with hydrating agents for balanced formulations
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