Name: Parathyroid Hormone (39-84), human
Brand: Creative Peptides
SKU: P03046
Availability: MadeToOrder

Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C154H246N34O51S1
M.W/Mr.	4984.6
Sequence	One Letter Code:APLAPRDAGSQRPRKKEDNVLVESHEKSLGEADKADVNVLTKAKSQ Three Letter Code:H-Ala-Pro-Leu-Ala-Pro-Arg-Asp-Ala-Gly-Ser-Gln-Arg-Pro-Arg-Lys-Lys-Glu-Asp-Asn-Val-Leu-Val-Glu-Ser-His-Glu-Lys-Ser-Leu-Gly-Glu-Ala-Asp-Lys-Ala-Asp-Val-Asn-Val-Leu-Thr-Lys-Ala-Lys-Ser-Gln-OH

Length	46
InChI	InChI=1S/C211H357N67O72/c1-97(2)78-128(169(310)234-91-150(288)241-121(56-62-152(290)291)172(313)239-109(21)167(308)257-136(86-157(300)301)186(327)247-113(42-24-30-66-212)170(311)238-108(20)168(309)258-138(88-159(304)305)192(333)274-163(104(15)16)203(344)267-134(84-149(222)287)191(332)273-162(103(13)14)202(343)266-131(81-100(7)8)189(330)275-164(111(23)283)204(345)253-114(43-25-31-67-213)171(312)237-107(19)166(307)243-115(44-26-32-68-214)177(318)268-140(93-280)194(335)256-127(208(349)350)55-61-147(220)285)259-195(336)141(94-281)269-178(319)118(47-29-35-71-217)246-179(320)123(57-63-153(292)293)249-185(326)132(82-112-89-229-96-235-112)260-196(337)142(95-282)270-182(323)125(59-65-155(296)297)254-200(341)160(101(9)10)271-188(329)130(80-99(5)6)265-201(342)161(102(11)12)272-190(331)133(83-148(221)286)261-187(328)137(87-158(302)303)263-181(322)124(58-64-154(294)295)248-174(315)117(46-28-34-70-216)244-173(314)116(45-27-33-69-215)245-175(316)119(48-36-72-230-209(223)224)251-198(339)145-53-41-77-278(145)207(348)126(50-38-74-232-211(227)228)255-180(321)122(54-60-146(219)284)250-193(334)139(92-279)242-151(289)90-233-165(306)106(18)236-184(325)135(85-156(298)299)262-176(317)120(49-37-73-231-210(225)226)252-197(338)144-52-40-76-277(144)206(347)110(22)240-183(324)129(79-98(3)4)264-199(340)143-51-39-75-276(143)205(346)105(17)218/h89,96-111,113-145,160-164,279-283H,24-88,90-95,212-218H2,1-23H3,(H2,219,284)(H2,220,285)(H2,221,286)(H2,222,287)(H,229,235)(H,233,306)(H,234,310)(H,236,325)(H,237,312)(H,238,311)(H,239,313)(H,240,324)(H,241,288)(H,242,289)(H,243,307)(H,244,314)(H,245,316)(H,246,320)(H,247,327)(H,248,315)(H,249,326)(H,250,334)(H,251,339)(H,252,338)(H,253,345)(H,254,341)(H,255,321)(H,256,335)(H,257,308)(H,258,309)(H,259,336)(H,260,337)(H,261,328)(H,262,317)(H,263,322)(H,264,340)(H,265,342)(H,266,343)(H,267,344)(H,268,318)(H,269,319)(H,270,323)(H,271,329)(H,272,331)(H,273,332)(H,274,333)(H,275,330)(H,290,291)(H,292,293)(H,294,295)(H,296,297)(H,298,299)(H,300,301)(H,302,303)(H,304,305)(H,349,350)(H4,223,224,230)(H4,225,226,231)(H4,227,228,232)/t105-,106-,107-,108-,109-,110-,111+,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,160-,161-,162-,163-,164-/m0/s1
InChI Key	DWVDAMCLTMJLAG-BLROTGJYSA-N

1. Multifunctional peptide-oligonucleotide conjugate promoted sensitive electrochemical biosensing of cardiac troponin I

2. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function

3. The effect of sex on immune responses to a homocitrullinated peptide in the DR4-transgenic mouse model of Rheumatoid Arthritis

4. Constitutive and inflammation-dependent antimicrobial peptides produced by epithelium are differentially processed and inactivated by the commensal Finegoldia magna and the pathogen Streptococcus pyogenes

5. Emerging applications of nanotechnology for diagnosis and therapy of disease: a review

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Angiotensin II Acetate

Angiotensin II is an octapeptide that produced from angiotensin I after the removal of two amino acids at the C-terminal by angiotensin-converting enzyme (ACE). Angiotensin II is mediated by AT1 and AT2 receptors, which are seven transmembrane glycoproteins with 30% sequence similarity.

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Aviptadil Acetate

Aviptadil, also known as vasoactive intestinal polypeptide (VIP), is a 28 amino acid neuropeptide that belongs to the glucagon-growth hormone-releasing factor secretion superfamily. Aviptadil acts as a potent systemic vasodilator and bronchodilator. It inhibits the proliferation of vascular and bronchial smooth muscle cells and decreases platelet aggregation. These biological effects are mediated by specific VIP receptors.

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Alarelin acetate

Alarelin acetate is a synthetic LH-RH agonist, and stimulates the release of FSH and LH from the pituitary gland. It is known for its induction of ovulation and used to treat endmometriosis.

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Somatostatin

Somatostatin is a tetradecapeptide which can suppress the growth hormone (GH) secretion and control the pituitary hormone secretion in human CNS.

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Terlipressin Acetate

Terlipressin acetate is a vasopressin analogue with potent vasoactive properties. Terlipressin acetate is a highly selective vasopressin V1 receptor agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin acetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin acetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research.

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Carperitide

Atrial Natriuretic Peptide (ANP) (1-28), human, porcine is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. ANP (1-28) inhibits endothelin-1 secretion in a dose-dependent way.

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Angiotensin II

Angiotensin II human (Angiotensin II) is a vasoconstrictor that mainly acts on the AT1 receptor. Angiotensin II human stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human also induces apoptosis.

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Antide

Antide acetate (Ac-AA10-NH2) is an LHRH antagonist and represses LH and FSH release from the pituitary gland. It shows a high antiovulatory activity and releases negligible histamine.

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Lanreotide Acetate

Lanreotide is a a synthetic cyclic octapeptide analogue of somatostatin. Lanreotide inhibits the secretion of growth hormone (GH) by binding to pituitary somatostatin receptors, and may inhibit the release of various other hormones, including thyroid stimulating hormone (TSH) and the gastroenteropancreatic hormones insulin, glucagon and gastrin.

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Terlipressin

Terlipressin is a synthetic triglycyllysine derivative of vasopressin with vasoconstrictive, antihemorrhagic, and antidiuretic properties. Upon intravenous administration, terlipressin, an inactive prodrug, is biotransformed to its active moiety, lysine vasopressin (LVP), a nonselective vasopressin analogue with affinity for vasopressin receptors V1 (V1a), V2 and V3 (V1b). As a V1 agonist, terlipressin increases systemic vascular resistance, particularly in the splanchnic area, resulting in a decrease of portal pressure. V1 binding also promotes platelet aggregation and glycogenolysis, while V3 binding induces adrenocorticotropic hormone (ACTH) secretion. Compared to vasopressin, terlipressin has a minimal effect on V2 receptors, which are responsible for promotion of water reabsorption in the collecting ducts of the kidney via stimulation of cyclic AMP production.

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