Trifluoroacetyl Tripeptide-2

Trifluoroacetyl Tripeptide-2 is a synthetic peptide consisting of three amino acids with a trifluoroacetyl group. It is utilized in cosmetic formulations for its ability to support skin conditioning and maintain skin's structural integrity. Suitable for a range of topical applications, Trifluoroacetyl Tripeptide-2 is compatible with various formulation types and aligns with global cosmetic regulations, making it a versatile choice for advanced skincare products.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Trifluoroacetyl Tripeptide-2(CAS 64577-63-5)

CAT No: CPC1617

CAS No:64577-63-5

Synonyms/Alias:64577-63-5;Tfa-VAL-TYR-VAL-OH;Trifluoroacetyl Tripeptide-2;Ecm-protect;N-(2,2,2-Trifluoroacetyl)-L-valyl-L-tyrosyl-L-valine;E6WT9V3SGO;IP 2000;L-Valine, N-(2,2,2-trifluoroacetyl)-L-valyl-L-tyrosyl-;(2S)-2-[[(2S)-3-(4-hydroxyphenyl)-2-[[(2S)-3-methyl-2-[(2,2,2-trifluoroacetyl)amino]butanoyl]amino]propanoyl]amino]-3-methylbutanoic acid;L-Valine, N-(trifluoroacetyl)-L-valyl-L-tyrosyl-;L-Valine, N-(N-(N-(trifluoroacetyl)-L-valyl)-L-tyrosyl)-;UNII-E6WT9V3SGO;CHEMBL3138715;SAVSLMGBKQKUAV-JYJNAYRXSA-N;HY-P5238;MFCD00056345;Trifluoroacetyl tripeptide-2 [INCI];FT92987;CS-0863818;L-Valine,N-(2,2,2-trifluoroacetyl)-L-valyl-L-tyrosyl-;(S)-2-((S)-3-(4-hydroxyphenyl)-2-((S)-3-methyl-2-(2,2,2-trifluoroacetamido)butanamido)propanamido)-3-methylbutanoic acid;

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C21H28F3N3O6
M.W/Mr.
475.5
Sequence
One Letter Code:VYV
Three Letter Code:Tfa-Val-Tyr-Val-OH
Functions
Trifluoroacetyl Tripeptide-2 regulates biological mechanisms involved in the aging process, reduces signs of aging including sagging, slacking and wrinkles and improves the skin firmness and elasticity.

Mechanism of Action (MOA)

Trifluoroacetyl Tripeptide-2 is a synthetic signaling peptide that interacts with cellular pathways involved in extracellular matrix (ECM) regulation. By mimicking specific amino acid sequences, this tripeptide modulates the activity of proteases such as matrix metalloproteinases (MMPs) and influences the expression of structural ECM proteins. Its biochemical action supports the maintenance of optimal ECM integrity, contributing to balanced cellular communication and homeostasis within the skin.

Trifluoroacetyl Tripeptide-2 is suitable for a variety of cosmetic formulations targeting skin care needs. - Incorporate into facial serums for daily skin care routines - Add to cream and lotion bases for enhanced product texture - Use in eye contour products for specialized formulations - Formulate into sheet masks and leave-on treatments - Blend with other peptides for multi-functional skin care systems - Suitable for both day and night care products

INCIName
Trifluoroacetyl Tripeptide-2
InChI
InChI=1S/C21H28F3N3O6/c1-10(2)15(27-20(33)21(22,23)24)18(30)25-14(9-12-5-7-13(28)8-6-12)17(29)26-16(11(3)4)19(31)32/h5-8,10-11,14-16,28H,9H2,1-4H3,(H,25,30)(H,26,29)(H,27,33)(H,31,32)/t14-,15-,16-/m0/s1
InChI Key
SAVSLMGBKQKUAV-JYJNAYRXSA-N
References
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