Triptorelin acetate is a potent LHRH agonist. It can result in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis. For most prostate cancers, they need the hormone testosterone in order to grow. Almost all testosterone in men is made by the testicles. Triptorelin stops the testicles from making testosterone. This reduces testosterone levels and may shrink the prostate cancer or stop it growing.
|57773-63-4 (net), 140194-24-7 (acetate)
|6-D-Tryptophan Luteinizing HorMone-Releasing Factor (Pig) Acetate;6-D-Tryptophan Luteinizing HorMone-Releasing Factor (Swine) Acetate;BIM 21003C;Decapeptyl-Depot;OvuGel;Triptorelin Acetate OR Triptorelin PaMoate;Triptorelin Acetate CAS 140194-24-7 (acetate);Triptelin Acetate
|Three Letter Code: Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 acetate salt
|Triptoreline as an antineoplastic (hormonal) is currently used in the treatment of prostatic cancer where therapy may be required over months or years. It is also used in the treatment of endometriosis and infertility.
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