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Ac-Val-Arg-Pro-Arg-AMC

Ac-Val-Arg-Pro-Arg-AMC is a fluorogenic substrate combining basic and hydrophobic residues for protease recognition. The AMC fluorophore provides high-sensitivity readout upon cleavage. Its sequence is optimized for kinetic and specificity analysis. Researchers employ it in enzyme profiling, substrate mapping, and mechanistic studies.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: C11103

CAS No:919515-51-8

Synonyms/Alias:Ac-Val-Arg-Pro-Arg-AMC Trifluoroacetate;919515-51-8;Ac-Val-Arg-Pro-Arg-AMC trifluoroacetate salt;(2S)-1-[(2S)-2-[[(2S)-2-acetamido-3-methylbutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid;MFCD18782519;DA-60802;FA110605;

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  • CMC information required for an IND
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M.F/Formula
C36H52F3N11O9
M.W/Mr.
839.9
Sequence
One Letter Code:VRPR
Three Letter Code:Ac-Val-Arg-Pro-Arg-AMC.TFA
InChI
InChI=1S/C34H51N11O7.C2HF3O2/c1-18(2)28(41-20(4)46)31(50)44-24(9-6-14-40-34(37)38)32(51)45-15-7-10-25(45)30(49)43-23(8-5-13-39-33(35)36)29(48)42-21-11-12-22-19(3)16-27(47)52-26(22)17-21;3-2(4,5)1(6)7/h11-12,16-18,23-25,28H,5-10,13-15H2,1-4H3,(H,41,46)(H,42,48)(H,43,49)(H,44,50)(H4,35,36,39)(H4,37,38,40);(H,6,7)/t23-,24-,25-,28-;/m0./s1
InChI Key
OPIFMWDQLNKKSM-XQVKXODCSA-N

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