Biotinoyl Tripeptide-1 is a synthetic peptide composed of biotin conjugated to a tripeptide sequence, designed for use in hair and lash care formulations. Recognized for its role in supporting the appearance of hair strength and density, it is suitable for inclusion in a range of topical products. Biotinoyl Tripeptide-1 is compatible with standard cosmetic formulation practices and meets regulatory requirements for global cosmetic applications.
CAT No: CPC1632
CAS No:299157-54-3
Synonyms/Alias:Biotinoyl tripeptide-1;299157-54-3;Biotin-GHK;UNII-O6380721VA;O6380721VA;Biotin Tripeptide-1(acetate);(2S)-2-[[(2S)-2-[[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-6-aminohexanoic acid;DTXSID70184028;L-Lysine, N-(5-((3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno(3,4-d)imidazol-4-yl)-1-oxopentyl)glycyl-L-histidyl-;Biotin Tripeptide-1;(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoyl)glycyl-L-histidyl-L-lysine;Biotinoyl-Tripeptide-1;BiotinoylTripeptide-1?;SCHEMBL1774374;DTXCID80106519;WCKVVODUWGBPQV-SOADLSRISA-N;BIOTINOYL TRIPEPTIDE-1 [INCI];AS-86628;DA-61674;HY-125616;CS-0092491;D92815;Q27285386;
Mechanism of Action (MOA)
Biotinoyl Tripeptide-1 is a synthetic signal peptide conjugated to biotin. It interacts with follicular and skin cells by mimicking naturally occurring peptide messengers, supporting extracellular matrix protein synthesis through upregulation of key genes associated with collagen and laminin production. This peptide may also influence cellular metabolic activity by enhancing biotin delivery, contributing to optimal cell function and maintenance within the skin and scalp environment.
Biotinoyl Tripeptide-1 can be incorporated into various cosmetic formulations to enhance product performance and versatility.
- Suitable for use in hair care products such as shampoos, conditioners, and serums- Can be added to eyelash and eyebrow enhancing formulations- Compatible with leave-in and rinse-off systems- Applicable in scalp care lotions and tonics- May be blended into brow gels and mascaras- Appropriate for use in both water-based and emulsion systems
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