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BMAP-18

BMAP-18 is a truncated form of the antimicrobial peptide BMAP-271. Bovine myeloid antimicrobial peptide-27(BMAP-27) belongs to the Cathelicidin family of peptides which displays rapid bactericidal activity against Staphylococcus aureus, Streptococcus uberis, and Escherichia coli. BMAP-27 is cytotoxic to human erythrocytes and neutrophils, although at higher than microbicidal concentrations1-3. BMAP-18 displays much higher cell selectivity as compared to parental BMAP-27 because of their decreased hemolytic activity and retained antimicrobial activity.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: AF3341

Synonyms/Alias:Bovine myeloid antimicrobial peptide-18

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cGMP Peptide
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  • CMC information required for an IND
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M.W/Mr.
2343
Sequence
One Letter Code: GRFKRFRKKFKKLFKKLS
Three Letter Code: Gly-Arg-Phe-Lys-Arg-Phe-Arg-Lys-Lys-Phe-Lys-Lys-Leu-Phe-Lys-Lys-Leu-Ser
Long-term Storage Conditions
BMAP-18 antimicrobial peptide is freely soluble in H2O
References
1. Haines L.R et al.,PLoS Negl Trop Dis.3(2) 373 (2009)
2. Cheng K et al mBio 7 01418-16 (2016)
3. Lee E.K et al Peptides 32(6), 1123-1130 (2011)

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