Cyclo(RGDyK)

Cyclo(RGDyK) is a cyclic derivative of RGD, potent, selective αVβ3 integrin inhibitor with an IC50 of 20 nM.

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CAT#	R1824
CAS	250612-42-1
Synonyms/Alias	(Cyclic Arg-Gly-Asp-D-Tyr-Lys)
Chemical Name	2,2,2-trifluoroacetic acid compound with 2-((1Z,2S,3Z,5R,6Z,8S,9Z,11S,12Z)-8-(4-aminobutyl)-11-(3-guanidinopropyl)-3,6,9,12,15-pentahydroxy-5-(4-hydroxybenzyl)-1,4,7,10,13-pentaazacyclopentadeca-3,6,9,12,15-pentaen-2-yl)acetic acid (2:1)
M.F/Formula	C31H43F6N9O12
Sequence	One Letter Code: Cyclic (RGDYK) Three Letter Code: Cyclic Arg-Gly-Asp-D-Tyr-Lys
Purity	>98%

CAT#	Product Name	Inquiry
R0982	P11	Inquiry
R1160	Acyl Carrier Protein (ACP) 65-74	Inquiry
R1915	Cyclo(-Leu-Pro)	Inquiry
R1960	Bremelanotide Acetate	Inquiry
R1417	HEX3	Inquiry

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Storage	Store at -20°C
Solubility	DMSO : ≥ 130 mg/mL (153.35 mM)
Shipping Condition	Evaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
InChI	InChI=1S/C27H41N9O8.2C2HF3O2/c28-10-2-1-4-18-24(42)34-17(5-3-11-31-27(29)30)23(41)32-14-21(38)33-20(13-22(39)40)26(44)36-19(25(43)35-18)12-15-6-8-16(37)9-7-15;23-2(4,5)1(6)7/h6-9,17-20,37H,1-5,10-14,28H2,(H,32,41)(H,33,38)(H,34,42)(H,35,43)(H,36,44)(H,39,40)(H4,29,30,31);2(H,6,7)/t17-,18-,19+,20-;;/m1../s1
InChI Key	CDDUWKKOPQABPG-WVSPKWNLSA-N
Canonical SMILES	C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCN=C(N)N)CCCCN)CC2=CC=C(C=C2)O)CC(=O)O.C(=O)(C(F)(F)F)O.C(=O)(C(F)(F)F)O