Cyclo(RGDyK) is a cyclic derivative of RGD, potent, selective αVβ3 integrin inhibitor with an IC50 of 20 nM.
CAT No: R1824
CAS No:250612-42-1
Synonyms/Alias:250612-42-1;Cyclic Arg-Gly-Asp-D-Tyr-Lys;Cyclo(RGDyK) trifluoroacetate;Cyclo(RGDyK);Cyclo(RGDyK) (trifluoroacetate);Cyclo(L-arginylglycyl-L-a-aspartyl-D-tyrosyl-L-lysyl) di2,2,2-Trifluoroacetic acid salt;2-[(2S,5R,8S,11S)-8-(4-aminobutyl)-11-[3-(diaminomethylideneamino)propyl]-5-[(4-hydroxyphenyl)methyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid;2,2,2-trifluoroacetic acid;MFCD20134101;CycloRGDyK trifluoroacetate;AKOS032945157;BS-16781;DA-52211;HY-100563;CS-0019707;C74288;Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) trifluoroacetate;Cyclo(L-arginylglycyl-L-|A-aspartyl-D-tyrosyl-L-lysyl) di2,2,2-Trifluoroacetic acid salt;[(2S,5R,8S,11S)-8-(4-aminobutyl)-11-(3-carbamimidamidopropyl)-5-[(4-hydroxyphenyl)methyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl]acetic acid; bis(trifluoroacetic acid);2,2,2-Trifluoroacetic acid compound with 2-((2S,5R,8S,11S)-8-(4-aminobutyl)-11-(3-guanidinopropyl)-5-(4-hydroxybenzyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid (2:1);Cyclo(L-arginylglycyl-L-(1/4)?-aspartyl-D-tyrosyl-L-lysyl) di2,2,2-Trifluoroacetic acid salt;
Chemical Name:2,2,2-trifluoroacetic acid compound with 2-((1Z,2S,3Z,5R,6Z,8S,9Z,11S,12Z)-8-(4-aminobutyl)-11-(3-guanidinopropyl)-3,6,9,12,15-pentahydroxy-5-(4-hydroxybenzyl)-1,4,7,10,13-pentaazacyclopentadeca-3,6,9,12,15-pentaen-2-yl)acetic acid (2:1)
2. Cationic cell-penetrating peptides are potent furin inhibitors
4. An Open-label, Single-center, Safety and Efficacy Study of Eyelash Polygrowth Factor Serum
5. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
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