DAMGO

DAMGO is a μ-opioid receptor (μ-OPR ) selective agonist.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
DAMGO(CAS 78123-71-4)

CAT No: R1322

CAS No:78123-71-4

Synonyms/Alias:DAMGO;DAGO;78123-71-4;glyol;Dagol;DAMGE;2-Ala-4-mephe-5-gly-enkephalin;Tyr-ala-gly-(nme)phe-gly-ol;RX 783006;(D-Ala(2)-mephe(4)-gly-ol(5))enkephalin;(2S)-2-amino-N-[(2R)-1-[[2-[[(2S)-1-(2-hydroxyethylamino)-1-oxo-3-phenylpropan-2-yl]-methylamino]-2-oxoethyl]amino]-1-oxopropan-2-yl]-3-(4-hydroxyphenyl)propanamide;Enkephalin, ala(2)-mephe(4)-gly(5)-;CHEBI:272;CHEMBL38874;Tyr-D-Ala-Gly-MePhe-Gly-ol;Enkephalin, alanyl(2)-methylphenylalanyl(4)-glycine(5)-;950492-85-0;[3H]DAMGO;Tyr-D-Ala-Gly-MePhe-Gly(ol);Tyr-D-Ala-Gly-NMe-Phe-Gly-ol;Tyr-D-Ala-Gly-(NMe)Phe-Gly-ol;Tyr-D-Ala-Gly-N(Me)Phe-Gly-ol;Tyr-D-Ala-Gly-N-Me-Phe-Gly-ol;Ala(2)-mephe(4)-gly-ol(5) enkephalin;Tyr-D-Ala-Gly-N-Methyl-Phe-Gly-ol;D-Ala2-MePhe4-Met(0)5-enkephalin-ol;Enkephalin, Ala(2)-MePhe(4)-Gly-ol(5)-;C26H35N5O6;H-Tyr-D-Ala-Gly-N-Me-Phe-Glycinol;[D-Ala2, NMe-Phe4, Gly-ol5]-enkephalin;2YM5VT3MNR;RX783006;Dagol;L-Phenylalaninamide, L-tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-Nalpha-methyl-;Tyr-DAla-Gly-MePhe-Gly-ol;SCHEMBL725750;GTPL1647;Tyr-D-Ala-Gly-NMePhe-Gly-ol;BDBM21015;H-Tyr-D-Ala-Gly-MePhe-Gly-ol;Tyr-D-Ala2-Gly-NMePhe-Gly-ol;DTXSID30228775;HPZJMUBDEAMBFI-WTNAPCKOSA-N;HY-P0210;Tyr-D-Ala-Gly-N(CH3)Phe-Gly-ol;H-Tyr-D-Ala-Gly-N(Me)Phe-Gly-ol;HB2409;AKOS024456435;NCGC00167303-01;(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]-methylamino]-N-(2-hydroxyethyl)-3-phenylpropanamide;AS-83278;BD173150;BD174973;DA-72545;CS-0021316;G12226;Q5204254;[tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephalin;3: PN: WO2009046859 PAGE: 98 CLAIMED PROTEIN;158: PN: US20030176421 PAGE: 54-55 CLAIMED PROTEIN;L-TYROSYL-D-ALANYLGLYCYL-N-(2-HYDROXYETHYL)-N.ALPHA.-METHYL-L-PHENYLALANINAMIDE;L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-Nalpha-methyl-L-phenylalaninamide;(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide;(2S)-2-amino-N-[(1R)-2-[[2-[[(1S)-1-benzyl-2-(2-hydroxyethylamino)-2-oxo-ethyl]-methyl-amino]-2-oxo-ethyl]amino]-1-methyl-2-oxo-ethyl]-3-(4-hydroxyphenyl)propanamide;(S)-2-amino-N-((R)-1-(2-(((S)-1-(2-hydroxyethylamino)-1-oxo-3-phenylpropan-2-yl)(methyl)amino)-2-oxoethylamino)-1-oxopropan-2-yl)-3-(4-hydroxyphenyl)propanamide;Benzenepropanimidic?acid, .alpha.-amino-4-hydroxy-N-[(1R,2Z)-2-hydroxy-2-[[2-[[(1S,2Z)-2-hydroxy-2-[(2-hydroxyethyl)imino]-1-(phenylmethyl)ethyl]methylamino]-2-oxoethyl]imino]-1-methylethyl]-, (.alpha.S)-;

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C26H35N5O6
M.W/Mr.
513.6
Sequence
One Letter Code:YAGFG
Three Letter Code:H-Tyr-D-Ala-Gly-N(Me)Phe-Gly-ol
Biological Activity
Highly selective peptide agonist for the μ opioid receptor.
Shipping Condition
Room temperature in continental US; may vary elsewhere.
InChI
InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1
InChI Key
HPZJMUBDEAMBFI-WTNAPCKOSA-N

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