DOTA-[Tyr3]-Octreotide Acid
Tetracosactide is a synthetic peptide, which corresponds to the first 24 amino acids of the naturally occurring hormone ACTH (adrenocorticotropic hormone). It stimulates the
adrenal cortex to produce corticosteroids, mineralocorticoids, and, to a lesser extent, androgens.
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| CAT# | R1831 |
| Explanation | DOTA-(Tyr3)-octreotate can be obtained through preparation of DOTA-containing peptides and radionucleotide complexes as antitumor agents for treating somatostatin postive tumor and metastasized tumors. |
| Synonyms/Alias | DOTATATE, DOTA-(Tyr³,Thr⁸)-Octreotide, DOTA-[Tyr3] Octreotide Acid (Octreotate); 4,7,10-Tricarboxymethyl-1,4,7,10-tetraaza-cyclododecan-1-yl-acetyl-D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr-OH acetate salt (Disulfide bond) |
| M.F/Formula | C65H90N14O19S2 |
| M.W/Mr. | 1435.63 |
| Sequence | 4,7,10-Tricarboxymethyl-1,4,7,10-tetraaza-cyclododecan-1-yl-acetyl-D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr-OH (disulfide bond) |
| Purity | 98% by HPLC |
| Source# | Synthetic |
Shipping Condition | Room temperature |
Canonical SMILES | CC(C1C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=C(C=C4)O)NC(=O)C(CC5=CC=CC=C5)NC(=O)CN6CCN(CCN(CCN(CC6)CC(=O)O)CC(=O)O)CC(=O)O)C(=O)NC(C(C)O)C(=O)O)O |
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