Deferasirox

Deferasirox (marketed as Exjade, Desirox, Defrijet, Desifer...) is an iron chelator. Its main use is to reduce chronic iron overload in patients who are receiving long-term blood transfusions for conditions such as beta-thalassemia and other chronic anemias. It is the first oral medication approved in the USA for this purpose.

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CAT#	10-101-115
CAS	201530-41-8
Synonyms/Alias	4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid; CGP-72670; ICL-670; ICL-670A
Chemical Name	4-[3,5-bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acid
M.F/Formula	C21H15N3O4
M.W/Mr.	373.3615
Labeling Target	Iron
Application	For the management or treatment of transfusional iron overload.
Appearance	Solid powder
Purity	>98% (or refer to the Certificate of Analysis)
Areas of Interest	Cardiovascular System & Diseases Pituitary & Hypothalamic Hormones
Disease	beta Thalassemia Chronic Iron Overload
Target	Bacterial

CAT#	Product Name	M.W	Molecular Formula	Inquiry
10-101-117	L-NMMA Acetate	248.28	C9H20N4O4	Inquiry
10-101-13	Elcatonin Acetate	3363.8	C148H244N42O47	Inquiry
10-101-40	Ornipressin	1042.19	C45H63N13O12S2	Inquiry
10-101-57	MOG (35-55)	2581.99	C118H177N35O29S	Inquiry
10-101-92	Nifalatide	673.74	C30H39N7O9S	Inquiry

CAT#	Product Name	M.W	Molecular Formula	Inquiry
10-101-20	Goserelin Acetate	1269.43	C59H84N18O14	Inquiry
10-101-59	Liraglutide	3751.2	C172H265N43O51	Inquiry
R1574	Octreotide	1019.24	C₄₉H₆₆N₁₀O₁₀S₂	Inquiry
10-101-139	Myrcludex B			Inquiry
10-101-285	Teduglutide	3752.08	C164H252N44O55S	Inquiry
R1847	Sermaglutide	4114	C187H291N45O59	Inquiry
R1961	Carbetocin	988.2	C45H69N11O12S	Inquiry

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Source#	Synthetic
Solubility	Soluble in DMSO, not in water
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Short-term Storage Conditions	Dry, dark and at 0 - 4 °C
Long-term Storage Conditions	-20 °C
Organism	Human
InChI	InChI=1S/C21H15N3O4/c25-17-7-3-1-5-15(17)19-22-20(16-6-2-4-8-18(16)26)24(23-19)14-11-9-13(10-12-14)21(27)28/h1-12,25-26H,(H,27,28)
InChI Key	BOFQWVMAQOTZIW-UHFFFAOYSA-N
Canonical SMILES	C1=CC=C(C(=C1)C2=NN(C(=N2)C3=CC=CC=C3O)C4=CC=C(C=C4)C(=O)O)O
Isomeric SMILES	C1=C/C(=C/2\N/C(=C\3/C=CC=CC3=O)/N(N2)C4=CC=C(C=C4)C(=O)O)/C(=O)C=C1
BoilingPoint	672.1±65.0 °C at 760 mmHg
ShelfLife	>2 years if stored properly
Melting Point	260-262ºC