β-Endorphin is an endogenous opioid peptide that acts as an agonist at μ-opioid receptors (μORs) and exhibits immunomodulatory, neuromodulatory, antidepressant, and antinociceptive/analgesic activities. In vivo, β-endorphin increases levels of B-cells and production of antibodies as well as secretion of IL-4 and proliferation of splenocytes, shifting the immune response toward Th2-specific mediators.
CAT No: R1885
CAS No: 77367-63-6
Synonyms/Alias: β-Lipotropin (61-91), rat; Proopiomelanocortin; POMC.
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M.F/Formula | C157H254N42O44S |
M.W/Mr. | 3466.02 |
Sequence | One Letter Code: YGGFMTSEKSQTPLVTLFKNAIIKNVHKKGQ Three Letter Code: Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Val-His-Lys-Lys-Gly-Gln |
Appearance | Whithe powder |
Purity | ≥97% (HPLC) |
Long-term Storage Conditions | Soluble in water. |
Shipping Condition | RT, or blue ice upon request. |
3. Implications of ligand-receptor binding kinetics on GLP-1R signalling
5. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists
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