Tetracosactide is a synthetic peptide, which corresponds to the first 24 amino acids of the naturally occurring hormone ACTH (adrenocorticotropic hormone). It stimulates the
adrenal cortex to produce corticosteroids, mineralocorticoids, and, to a lesser extent, androgens.
|Synonyms/Alias||N6-(Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-.alpha.-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide Cyclic (16)-Disulfide; Integrelin; Integrilin; Intrifiban|
|Application||An arginine-glycine-aspartate-mimetic, reversibly binds to platelets to reduce the risk of cardiac ischemic events.|
|Appearance||White to Off-White Solid|
|Biological Activity||Glycoprotein (GP) IIb/IIIa inhibitor. Reversibly and competitively binds to GPIIa/IIIb on platelets, inhibiting aggregation.|
||Long-term Storage Conditions||Soluble to 5 mg/ml in water
||Shipping Condition||Room temperature in continental US; may vary elsewhere.
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