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Exendin (9-39) is a competitive GLP-1 (glucagon-like peptide 1) receptor antagonist. Exendin (9-39) blocks the stimulatory action of GLP-1 amide, exendin-3 and exendin-4 on cAMP production in pancreatic acini. In addition, exendin (9-39) was showed not to interfer the insulin normal secretion.
CAT No: 10-101-83
CAS No: 133514-43-9 (net)
Synonyms/Alias: Ex4 peptide; Exendin9-39
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M.F/Formula | C149H234N40O47S |
M.W/Mr. | 3369.8 |
Sequence | H-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 acetate salt |
Application | Exendin (9-39) is a GLP-1 (glucagon-like peptide-1) receptor antagonist and a competitive inhibitor of exendin-3 and exendin-4. |
Areas of Interest | Diabetes |
Source# | Synthetic |
Solubility | −20°C |
1. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
3. High fat diet and GLP-1 drugs induce pancreatic injury in mice
4. Myotropic activity of allatostatins in tenebrionid beetles
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