Hexapeptide-10 is a synthetic peptide composed of six amino acids, designed for use in advanced skin care formulations. Recognized for its role in supporting skin structure, it is commonly incorporated into products targeting the appearance of skin firmness and smoothness. Hexapeptide-10 is suitable for a wide range of cosmetic applications, including facial creams, serums, and anti-aging formulations, and is compatible with global regulatory requirements for cosmetic ingredients.
CAT No: CPC1619
CAS No:146439-94-3
Synonyms/Alias:Hexapeptide-10;H-Ser-ile-lys-val-ala-val-OH;146439-94-3;Serilesine;L-Valine, L-seryl-L-isoleucyl-L-lysyl-L-valyl-L-alanyl-;Hexapeptide-10 [INCI];UNII-W9RS1K7T9I;W9RS1K7T9I;SIKVAV (acetate);L-Valine, N-(N-(N-(N2-(N-L-seryl-L-isoleucyl)-L-lysyl)-L-valyl)-L-alanyl)-;L-seryl-L-isoleucyl-L-lysyl-L-valyl-L-alanyl-L-valine;(2S)-2-[[(2s)-2-[[(2s)-2-[[(2s)-6-amino-2-[[(2s,3s)-2-[[(2s)-2-amino-3-hydroxypropanoyl]amino]-3-methylpentanoyl]amino]hexanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-3-methylbutanoic acid;Hexapeptide-10?;SCHEMBL2119473;OFGVZFQUFJYSGS-CPDXTSBQSA-N;AKOS030573307;seryl-isoleucyl-lysyl-valyl-alanyl-valine;DS-19756;DS-017466;HY-125553;CS-0092199;C72781;Q27292509;
Mechanism of Action (MOA)
Hexapeptide-10 is a synthetic matrikine peptide that interacts with specific cell surface receptors to support cell-to-cell and cell-to-extracellular matrix (ECM) communication. By mimicking sequences found in laminin, Hexapeptide-10 is associated with the modulation of integrin signaling pathways, which can influence cellular adhesion and ECM organization. This peptide's activity is linked to the regulation of key proteins involved in maintaining the structural integrity of the skin's architecture.
Hexapeptide-10 is suitable for incorporation into a variety of cosmetic formulations targeting skin care.
- Facial serums for daily skin conditioning- Lightweight emulsions such as lotions and creams- Eye contour products for delicate skin areas- Leave-on masks for enhanced skin care routines- Gel-based moisturizers and hydrating products- Sheet masks and fabric-based delivery systems
1. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
2. The spatiotemporal control of signalling and trafficking of the GLP-1R
4. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
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