KYL

EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM), which inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM), prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. It shows neuroprotective effect.

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CAT#R0975
CAS676657-00-4
M.F/FormulaC74H108N14O17
M.W/Mr.1465.75
SequenceKYLPYWPVLSSL
Labeling TargetEphA4 receptor tyrosine kinase
ActivityInhibitor
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