LXW7

Tetracosactide is a synthetic peptide, which corresponds to the first 24 amino acids of the naturally occurring hormone ACTH (adrenocorticotropic hormone). It stimulates the adrenal cortex to produce corticosteroids, mineralocorticoids, and, to a lesser extent, androgens.

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CAT#R1876
ExplanationLXW7, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin αvβ3 inhibitor. LXW7 has a high binding affinity to αvβ3 integrin with an IC50 of 0.68 μM. LXW7 increases the phosphorylation of VEGFR-2 and activation of ERK1/2.
M.F/FormulaC29H48N12O12S2
M.W/Mr.820.89
SequenceOne Letter Code: CGRGDDVC
Three Letter Code: Cys-Gly-Arg-Gly-Asp-Asp-Val-Cys-NH2 (Disulfide bridge:Cys1-Cys8)
Purity>98 %
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