Pentagastrin

Tetracosactide is a synthetic peptide, which corresponds to the first 24 amino acids of the naturally occurring hormone ACTH (adrenocorticotropic hormone). It stimulates the adrenal cortex to produce corticosteroids, mineralocorticoids, and, to a lesser extent, androgens.

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CAT#10-101-95
ExplanationPentagastrin is a synthetic pentapeptide that has effects like gastrin. When given parenterally it stimulates the secretion of gastric acid, pepsin and intrinsic factor.
Synonyms/AliasAY 6608; ICI 50123; NSC 367746; Boc-(β-Ala13)-Gastrin (13-17); Boc-β-Ala-CCK-4; Peptavlon; D01631
M.F/FormulaC37H49N7O9S
M.W/Mr.767.9
SequenceOne Letter Code: Boc-β-AWMDF
Three Letter Code: Boc-β-Ala-Trp-Met-Asp-Phe-NH2
ApplicationPentagastrin has been used as a diagnostic aid as the pentagastrin-stimulated calcitonin test. Pentagastrin is also used as a stimulation test to elevate of several hormones, such as serotonin.
AppearanceSolid powder
Purity>98% (or refer to the Certificate of Analysis)
ActivityAgonist
TargetCholecystokinin Receptor
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