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Eptifibatide, is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class. Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri). It belongs to the class of the so-called RGD (arginine-glycine-aspartate)-mimetics and reversibly binds to platelets.
| CAT# | 10-101-15 |
| CAS | 188627-80-7 (net) |
| Synonyms/Alias | Eptifibatide; Integrilin; CHEBI:291902 |
| Chemical Name | 2-[20-carbamoyl-12-[4-(diaminomethylideneamino)butyl]-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,22-hexaoxo-17,18-dithia-1,4,7,10,13,21-hexazabicyclo[21.3.0]hexacosan-6-yl]acetic acid |
| M.F/Formula | C35H49N11O9S2 |
| M.W/Mr. | 832.4 |
| Sequence | [Mpa1-Cys6] Mpa-Har-Gly-Asp-Trp-Pro-Cys-NH2 |
| Labeling Target | Integrin |
| Application | Eptifibatide is used to treat myocardial infarction and acute coronary syndrome. |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Activity | Inhibitor |
| Areas of Interest | Cardiovascular System & Diseases Pituitary & Hypothalamic Hormones |
| Functions | Virus receptor activity |
| Disease | Acute coronary syndrome; Percutaneous coronary intervention |
| Target | Integrin |
| Source# | Synthetic | Solubility | Soluble in DMSO | Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. | Short-term Storage Conditions | Dry, dark and at 0 - 4 °C | Long-term Storage Conditions | -20 °C | Organism | Human | InChI | InChI=1S/C35H49N11O9S2/c36-30(51)25-18-57-56-13-10-27(47)42-22(8-3-4-11-39-35(37)38)31(52)41-17-28(48)43-23(15-29(49)50)32(53)44-24(14-19-16-40-21-7-2-1-6-20(19)21)34(55)46-12-5-9-26(46)33(54)45-25/h1-2,6-7,16,22-26,40H,3-5,8-15,17-18H2,(H2,36,51)(H,41,52)(H,42,47)(H,43,48)(H,44,53)(H,45,54)(H,49,50)(H4,37,38,39) | InChI Key | CZKPOZZJODAYPZ-UHFFFAOYSA-N | Canonical SMILES | C1CC2C(=O)NC(CSSCCC(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N2C1)CC3=CNC4=CC=CC=C43)CC(=O)O)CCCCN=C(N)N)C(=O)N | BoilingPoint | N/A | ShelfLife | >2 years if stored properly | Melting Point | 92-98 °C |
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