Zonisamide
Zonisamide is a sulfonamide anticonvulsant approved for use as an adjunctive therapy in adults with partial-onset seizures, infantile spasm, mixed seizure types of Lennox–Gastaut syndrome, myoclonic, and generalized tonic clonic seizure.
Online Inquiry
| CAT# | 10-101-130 |
| CAS | 68291-97-4 |
| Synonyms/Alias | AD-810; CI-912; PD-110843; 1,2-Benzisoxazole-3-methanesulfonamide; 3-(Sulfamoylmethyl)-1,2-benzisoxazole; Benzo[d]isoxazol-3-yl-methanesulfonamide |
| M.F/Formula | C8H8N2O3S |
| M.W/Mr. | 212.23 |
| Labeling Target | Carbonic anhydrase;
Voltage-dependent T-type calcium channel;
Sodium channel protein type 1 subunit alpha |
| Application | Zonisamide has been used in the treatment in Epilepsy & Parkinson's disease & Tardive dyskinesia & Obesity & Migraines & Bipolar depression. |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Activity | Inhibitor |
| Biological Activity | Zonisamide (AD 810) is an inhibitor of zinc enzyme carbonic anhydrase (CA), with Kis of 35.2 nM and 20.6 nM for human mitochondrial isozyme hCA II and hCA V, respectively. Zonisamide has antiepileptic activity. |
| Areas of Interest | Cardiovascular System & Diseases
Pituitary & Hypothalamic Hormones |
| Functions | Vasopressin receptor activity |
| Target | Carbonic Anhydrase |
| Source# | Synthetic |
Solubility | Soluble in DMSO, not in water |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Short-term Storage Conditions | Dry, dark and at 0 - 4 °C |
Long-term Storage Conditions | -20 °C |
Organism | Human |
InChI | InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12) |
InChI Key | UBQNRHZMVUUOMG-UHFFFAOYSA-N |
BoilingPoint | 457.2±47.0 °C at 760 mmHg |
ShelfLife | >2 years if stored properly |
Melting Point | 275°C dec. |
Write a review
Ask a question
My Review for Zonisamide
Required fields are marked with *
×
Ask a Question for Zonisamide
Required fields are marked with *
×
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
