Vancomycin is an antibacterial compound obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly.
CAT# | 10-101-103 |
CAS | 1404-90-6 |
Background | Vancomycin is a branched tricyclic glycosylated peptide with bactericidal activity against most organisms and bacteriostatic effect on enterococci. At a site different from that of penicillins and cephalosporins, vancomycin binds tightly to the D-alanyl-D-alanine portion of cell wall precursors, thereby interfering with bacterial cell wall synthesis. This leads to activation of bacterial autolysins that destroy the cell wall by lysis. Vancomycin may also alter the permeability of bacterial cytoplasmic membranes and may selectively inhibit RNA synthesis. |
Synonyms/Alias | Vancocin; Vancomycine; Vancomycinum; Vancomicina; HSDB 3262; Vancomycin; EINECS 215-772-6; LS-161387; LS161387; Diatracin; Vancocine |
M.F/Formula | C66H75Cl2N9O24 |
M.W/Mr. | 1449.25 |
Labeling Target | D-Ala-D-Ala moiety of NAM/NAG peptide subunits of peptidoglycan |
Application | Vancomycin is an antibiotic used to treat a number of bacterial infections. It is a member of the glycopeptide antibiotic class and is effective mostly against Gram-positive bacteria. |
Appearance | White to off-white solid powder |
Purity | >98% (or refer to the Certificate of Analysis) |
Biological Activity | Vancomycin is an antibiotic for the treatment of bacterial infections. |
Areas of Interest | Cardiovascular System & Diseases Pituitary & Hypothalamic Hormones |
Target | Antimicrobial |
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