Caspofungin is an antifungal drug, the first of a new class termed the echinocandins from Merck & Co., Inc. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal cell wall. Caspofungin is administered intravenously.
Caspofungin is an antifungal drug, and used for the treatment of esophageal candidiasis and invasive aspergillosis in patients who are refractory to or intolerant of other therapies.
Areas of Interest
1,3-beta-d-glucan synthase activity
Candidiasis of the esophagus; Candidemia; Intra-Abdominal Candida Abscess; Candida Pleural Space Infection
Aspergillus niger (strain CBS 513.88 / FGSC A1513)