An impurity of Eptifibatide. Eptifibatide, is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class. Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri). It belongs to the class of the so-called RGD (arginine-glycine-aspartate)-mimetics and reversibly binds to platelets.
Registration of APIs CMC information required for an IND
IND and NDA support Drug master files (DMF) filing
M.F/Formula | C35H48N10O10S2 |
M.W/Mr. | 832.95 |
Sequence | deamino-Cys(1)-hArg-Gly-Asp-Trp-Pro-Cys(1)-OH |
2. Cationic cell-penetrating peptides are potent furin inhibitors
3. Store-operated Ca2+ entry sustains the fertilization Ca2+ signal in pig eggs
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