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Angiotensin I Human

Angiotensin I Human is a synthetic peptide corresponding to the human angiotensin I sequence, designed for advanced cosmetic formulations. As a bioactive peptide, it is utilized in research and development of skin care products targeting the appearance of skin vitality and resilience. Its inclusion supports innovative approaches to cosmetic formulations where peptides play a role in optimizing skin condition and overall product performance. Suitable for use in compliance with global cosmetic regulations.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CPC1697

CAS No:70937-97-2

Synonyms/Alias:Angiotensin I human acetate salt hydrate;70937-97-2;(Ile5)-Angiotensin I acetate;Angiotensin I, diacetate (salt);VCA93797;

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C64H95N17O17
M.W/Mr.
1374.5
Sequence
One Letter Code:DRVYIHPFHL
Three Letter Code:H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-OH.CH3CO2H.H2O
Appearance
White to off white powder
Purity
≥90% (HPLC)

Mechanism of Action (MOA)

Angiotensin I Human is a linear decapeptide classified as a signaling peptide. Upon topical application, it may interact with skin cell receptors involved in the renin-angiotensin system, influencing pathways associated with cellular communication and homeostasis. This peptide can modulate the local environment by affecting the activity of endogenous enzymes such as angiotensin-converting enzyme (ACE), thereby participating in the regulation of signaling cascades relevant to skin physiology.

Angiotensin I Human is suitable for incorporation into a variety of cosmetic formulations.

- Add to serums targeting the appearance of mature skin
- Include in emulsions such as creams and lotions
- Formulate within eye area products
- Blend into hydrogel or bio-cellulose sheet masks
- Combine with other peptides in multi-functional blends
- Integrate into leave-on treatments for facial care

Length
10
Shipping Condition
RT, or blue ice upon request.
InChI
InChI=1S/C62H89N17O14.C2H4O2.H2O/c1-7-35(6)51(78-56(87)44(25-37-17-19-40(80)20-18-37)74-58(89)50(34(4)5)77-53(84)42(15-11-21-68-62(64)65)71-52(83)41(63)28-49(81)82)59(90)75-46(27-39-30-67-32-70-39)60(91)79-22-12-16-48(79)57(88)73-43(24-36-13-9-8-10-14-36)54(85)72-45(26-38-29-66-31-69-38)55(86)76-47(61(92)93)23-33(2)3;1-2(3)4;/h8-10,13-14,17-20,29-35,41-48,50-51,80H,7,11-12,15-16,21-28,63H2,1-6H3,(H,66,69)(H,67,70)(H,71,83)(H,72,85)(H,73,88)(H,74,89)(H,75,90)(H,76,86)(H,77,84)(H,78,87)(H,81,82)(H,92,93)(H4,64,65,68);1H3,(H,3,4);1H2/t35-,41-,42-,43-,44-,45-,46-,47-,48-,50-,51-;;/m0../s1
InChI Key
GQMWNZUFNXZMDE-TYQYNJATSA-N
Canonical SMILES
CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CN=CN4)C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N.CC(=O)O.O

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