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Antazoline Phosphate, as phosphate salt of antazoline, is the histamine H1 receptor antagonist. It acts as an antihistamine. Generally by combinating with a decongestant, antazoline phosphate is applied topically to relieve the symptoms of allergic conjunctivitis.
| CAT# | 10-101-109 |
| CAS | 91-75-8 (net), 154-68-7 (phosphate) |
| Synonyms/Alias | 2-(N-Phenyl-N-benzyl-aminomethyl)imidazoline . phosphate; 2-[(N-Benzylanilino)methyl]-2-imidazoline . phosphate; 4,5-Dihydro-N-phenyl-N-(phenylmethyl)-1H-imidazole-2-methanamine . phosphate |
| Chemical Name | N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline;phosphoric acid |
| M.F/Formula | C17H22N3O4P |
| M.W/Mr. | 265.36 (net), 363.35 (phosphate) |
| Labeling Target | Histamine Receptor |
| Application | Conjunctivitis |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Activity | Antagonist |
| Areas of Interest | Neurological Disease |
| Target | Histamine H1 receptor |
| Solubility | Soluble in DMSO, not in water | Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. | Short-term Storage Conditions | Dry, dark and at 0 - 4 °C | Long-term Storage Conditions | -20 °C | Format | neat | InChI | InChI=1S/C17H19N3.H3O4P/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16;1-5(2,3)4/h1-10H,11-14H2,(H,18,19);(H3,1,2,3,4) | InChI Key | DUIGUKRYYAGJAF-UHFFFAOYSA-N | Canonical SMILES | C1CN=C(N1)CN(CC2=CC=CC=C2)C3=CC=CC=C3.OP(=O)(O)O | BoilingPoint | 235-236 °C(lit.) | ShelfLife | >2 years if stored properly | Melting Point | 120-122ºC |
| CAT# | Product Name | M.W | Molecular Formula | Inquiry |
|---|---|---|---|---|
| 10-101-108 | Antazoline Hydrochloride Ph. Eur. | 265.36 (net), 301.82 (hydrochloride) | C17H20ClN3 | Inquiry |
| 10-101-110 | Antazoline Sulfate | 363.35 | C17H19N3·H2O4S | Inquiry |
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