Darifenacin Hydrobromide
Darifenacin hydrobromide is used to treat people who have urinary problems such as urinary incontinence, urinary urgency or urinary frequency which are caused by an overactive bladder. It works by preventing spasms of the bladder muscle. This can help to reduce the episodes of urinary incontinence, the frequency of urination or reduce the feeling of urgency that bladder spasms can cause.
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| CAT# | 10-101-114 |
| CAS | 133099-04-4 (net), 133099-07-7 (hydrobromide) |
| Synonyms/Alias | 2-[(3S)-1-[2-(2,3-Dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide hydrobromide |
| Chemical Name | 2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide;hydrobromide |
| M.F/Formula | C28H31BrN2O |
| M.W/Mr. | 507.5 |
| Labeling Target | Muscarinic acetylcholine receptor |
| Application | Overactive bladder |
| Activity | Antagonist |
| Areas of Interest | Neurological Disease |
| Functions | Receptor activity |
| Disease | Urgent desire to urinate;
Urge incontinence of urine;
Bladder muscle dysfunction - overactive;
Increased Urinary Frequency; |
| Target | mAChR |
| Source# | Synthetic |
Long-term Storage Conditions | −20°C |
Organism | Human |
InChI | InChI=1S/C28H30N2O2.BrH/c29-27(31)28(23-7-3-1-4-8-23,24-9-5-2-6-10-24)25-14-17-30(20-25)16-13-21-11-12-26-22(19-21)15-18-32-26;/h1-12,19,25H,13-18,20H2,(H2,29,31);1H/t25-;/m1./s1 |
InChI Key | UQAVIASOPREUIT-VQIWEWKSSA-N |
Canonical SMILES | C1CN(CC1C(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)N)CCC4=CC5=C(C=C4)OCC5.Br |
Isomeric SMILES | C1CN(C[C@@H]1C(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)N)CCC4=CC5=C(C=C4)OCC5.Br |
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