Decanoyl-Arg-Val-Lys-Arg-chloromethylketone

Decanoyl-RVKR-CMK is highly specific, potent, irreversible, and cell-permeable competitive subtilisin/kex2p-like proprotein convertase inhibitor. It can inhibit activity of all seven convertases (pc1, pc2, pc4, pace4, pc5, pc7 and furin). It is used as a useful antiviral agent.

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CAT#	R0888
CAS	150113-99-8
Synonyms/Alias	Decanoyl-RVKR-CMK; Decanoyl-Arg-Val-Lys-Arg-CMK; Furin Convertase Inhibitor (Chloromethylketone)
M.F/Formula	C34H66ClN11O5
M.W/Mr.	744.42
Sequence	Decanoyl-Arg-Val-Lys-Arg-CMK
Labeling Target	Proprotein convertase
Appearance	Crystalline solid
Purity	>98%
Activity	Inhibitor

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Source#	Synthetic
Storage	-20°C
Long-term Storage Conditions	-20 °C
InChI	InChI=1S/C34H66ClN11O5/c1-4-5-6-7-8-9-10-18-28(48)43-25(17-14-21-42-34(39)40)31(50)46-29(23(2)3)32(51)45-26(15-11-12-19-36)30(49)44-24(27(47)22-35)16-13-20-41-33(37)38/h23-26,29H,4-22,36H2,1-3H3,(H,43,48)(H,44,49)(H,45,51)(H,46,50)(H4,37,38,41)(H4,39,40,42)/t24-,25-,26-,29-/m0/s1
InChI Key	NHBJTTGFHCHQHS-VZTVMPNDSA-N
Isomeric SMILES	CCCCCCCCCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C(N)N)C(=O)CCl
BoilingPoint	N/A
Melting Point	N/A