Felypressin Acetate

Tetracosactide is a synthetic peptide, which corresponds to the first 24 amino acids of the naturally occurring hormone ACTH (adrenocorticotropic hormone). It stimulates the adrenal cortex to produce corticosteroids, mineralocorticoids, and, to a lesser extent, androgens.

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ExplanationFelypressin is a Vasopressin 1 agonist, and will thus have effects at all Arginine vasopressin receptor 1As. It physiologically effects on vascular SMC's due to the form in which it is administered. Its receptors are found in various sites around the body. The major points include the CNS, Liver, Anterior Pituitary, Muscle (both vascular and non-vascular smooth muscle), and Platelets (CLAMP).
Synonyms/AliasOctapressin; Octopressin; Phelypressin; Phenylalanine Lysine Vasopressin; PLV-2; Vasopressin, Phenylalanyl-Lysyl; DL-cysteinyl-DL-phenylalanyl-DL-phenylalanyl-DL-glutaminyl-DL-asparagyl-DL-cysteinyl-DL-prolyl-DL-lysyl-glycinamide (1->6)-disulfide acetic acid
Chemical Nameacetic acid;N-[6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]-1-[19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13,16-dibenzyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
SequenceOne Letter Code: CFFQNCPKG
Three Letter Code: H-DL-Cys(1)-DL-Phe-DL-Phe-DL-Gln-DL-Asn-DL-Cys(1)-DL-Pro-DL-Lys-Gly-NH2.CH3CO2H
ApplicationFelypressin is a non-catecholamine vasoconstrictor that is chemically related to vasopressin, the posterior pituitary hormone. It is added to some local anaesthetics.
TargetVasopressin Receptor
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