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Foxy-5

Foxy-5 has been used in trials studying the treatment of Prostate Cancer, Colorectal Cancer, Metastatic Colon Cancer, Metastatic Breast Cancer, and Metastatic Prostate Cancer.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Foxy-5(CAS 881188-51-8)

CAT No: R1861

CAS No:881188-51-8

Synonyms/Alias:FOXY-5;881188-51-8;FOXY5;Foxy 5;N-Formyl-Met-Asp-Gly-Cys-Glu-Leu;WNT-5A derived hexapeptide FOXY-5;CBZ9UL0ARB;UNII-CBZ9UL0ARB;L-Leucine,N-formyl-L-methionyl-L-a-aspartylglycyl-L-cysteinyl-L-a-glutamyl-;L-Leucine, N-formyl-L-methionyl-L-alpha-aspartylglycyl-L-cysteinyl-L-alpha-glutamyl-;(2S)-2-[[(2S)-4-carboxy-2-[[(2R)-2-[[2-[[(2S)-3-carboxy-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]propanoyl]amino]acetyl]amino]-3-sulfanylpropanoyl]amino]butanoyl]amino]-4-methylpentanoic acid;(2S,5S,8R,14S)-5-(2-carboxyethyl)-14-((S)-2-formamido-4-(methylthio)butanamido)-2-isobutyl-8-(mercaptomethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazahexadecanedioic acid;L-LEUCINE, N-FORMYL-L-METHIONYL-L-.ALPHA.-ASPARTYLGLYCYL-L-CYSTEINYL-L-.ALPHA.-GLUTAMYL-;Wnt5a hexapeptide;(2S)-2-((2S)-4-carboxy-2-((2R)-2-(2-((2S)-3-carboxy-2-((2S)-2-formamido-4-(methylsulfanyl)butanamido)propanamido)acetamido)-3-sulfanylpropanamido)butanamido)-4-methylpentanoic acid;(2S)-2-[(2S)-4-carboxy-2-[(2R)-2-{2-[(2S)-3-carboxy-2-[(2S)-2-formamido-4-(methylsulfanyl)butanamido]propanamido]acetamido}-3-sulfanylpropanamido]butanamido]-4-methylpentanoic acid;Foxy 5 TFA;FOXY 5 [WHO-DD];FOXY-5 [WHO-DD];Foxy-5(Wnt5a peptide mimetic);CHEMBL4297281;SCHEMBL23477401;formyl-Met-Asp-Gly-Cys-Glu-Leu;Foxy-5(Wnt5a peptide mimetic)?;CHEBI:125492;Wnt-5a Mimic Hexapeptide Foxy-5;EX-A4066;HY-P1416;AKOS025147366;CCG-208076;DB13034;DA-73540;CS-0033287;NS00072887;BRD-K13005598-001-01-5;BRD-K13005598-001-02-3;Q27216112;

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C26H42N6O12S2
M.W/Mr.
694.8
Sequence
One Letter Code:MDGCEL
Three Letter Code:For-Met-Asp-Gly-Cys-Glu-Leu-OH
Purity
> 95%
Activity
Wnt5a peptide mimetic. Impairs migration and invasion of 4T1 breast cancer cells in vitro. Also inhibits metastasis of inoculated 4T1 cells in mice.
Source#
Synthetic
Long-term Storage Conditions
Soluble to 1 mg/ml in PBS (pH 7.4); 10 mM in DMSO
Shipping Condition
Wet ice in continental US; may vary elsewhere
InChI
InChI=1S/C26H42N6O12S2/c1-13(2)8-17(26(43)44)32-24(41)15(4-5-20(35)36)30-25(42)18(11-45)29-19(34)10-27-22(39)16(9-21(37)38)31-23(40)14(28-12-33)6-7-46-3/h12-18,45H,4-11H2,1-3H3,(H,27,39)(H,28,33)(H,29,34)(H,30,42)(H,31,40)(H,32,41)(H,35,36)(H,37,38)(H,43,44)/t14-,15-,16-,17-,18-/m0/s1
InChI Key
WFZPJYYCTSHDJI-ATIWLJMLSA-N

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