Palmitoyl Pentapeptide-4 is a synthetic peptide composed of five amino acids linked to a palmitic acid chain to enhance skin penetration. Widely utilized in cosmetic formulations, it is recognized for its ability to support skin conditioning and improve the appearance of skin texture. Suitable for inclusion in anti-aging, moisturizing, and skin care products, Palmitoyl Pentapeptide-4 is compatible with global cosmetic regulations and various formulation types.
CAT No: CPC1601
CAS No:214047-00-4
Synonyms/Alias:214047-00-4;Palmitoyl pentapeptide-3;Matrixyl;L-Serine, N2-(1-oxohexadecyl)-L-lysyl-L-threonyl-L-threonyl-L-lysyl-;Palmitoyl Pentapeptide-4;(2S,5S,8S,11S,14S)-5,14-Bis(4-aminobutyl)-8,11-bis((R)-1-hydroxyethyl)-2-(hydroxymethyl)-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazahentriacontan-1-oic acid;Oristar popp;Lipopentapeptide 3;N2-(1-oxohexadecyl)-L-lysyl-L-threonyl-L-threonyl-L-lysyl-L-serine;Palmitoyl pentapeptide 4;PAL-Lys-Thr-Thr-Lys-Ser;PALMITOYL PENTAPEPTIDE;(2S)-2-[[(2S)-6-amino-2-[[(2S,3R)-2-[[(2S,3R)-2-[[(2S)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]hexanoyl]amino]-3-hydroxypropanoic acid;Pal-KTTKS;MFCD09842091;C39H75N7O10;Palmitoyl pentapeptide?;Wsgcrsmlxfhgrm-devhwetnsa-N;KK181SM5JG;SCHEMBL352420;CHEMBL451881;Palmitoyl pentapeptide-4 [INCI];HY-P0045;AKOS027326911;214047-00-4( free base form);AS-72359;FP138115;Palmitoyl pentapeptide trifluoroacetic acid;CS-0005656;C74034;A902886;(2S)-2-[(2S)-6-AMINO-2-[(2S,3R)-2-[(2S,3R)-2-[(2S)-6-AMINO-2-HEXADECANAMIDOHEXANAMIDO]-3-HYDROXYBUTANAMIDO]-3-HYDROXYBUTANAMIDO]HEXANAMIDO]-3-HYDROXYPROPANOIC ACID;(2S,5S,8S,11S,14S)-5,14-Bis(4-aminobutyl)-8,11-bis((R)-1-hydroxyethyl)-2-(hydroxymethyl)-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaaZahentriacontan-1-oic acid (Palmitoyl-Lys-Thr-Thr-Lys-Ser-OH);606-757-9;
Mechanism of Action (MOA)
Palmitoyl Pentapeptide-4 is a matrikine-type signaling peptide that interacts with skin cells by mimicking fragments of extracellular matrix proteins. Upon topical application, it is recognized by fibroblast receptors, supporting cellular communication pathways involved in the maintenance of the extracellular matrix. This peptide may influence the expression of key matrix components, such as collagen, fibronectin, and hyaluronic acid, thereby contributing to the skin's structural integrity through biochemical signaling processes.
Palmitoyl Pentapeptide-4 is suitable for incorporation into a variety of topical cosmetic formulations.
- Facial creams and lotions- Eye contour serums and gels- Overnight masks and leave-on treatments- Lightweight emulsions for daily skincare- Sheet masks and hydrogel patches- Primer formulations for pre-makeup application
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