Renin 390 FRET Substrate I

Name: Renin 390 FRET Substrate I
Brand: Creative Peptides
Rating: 5 (1 reviews)

Renin 390 FRET Substrate I is a peptide-based Förster resonance energy transfer substrate designed around a renin-cleavage motif. Donor and acceptor fluorophores permit real-time monitoring of enzymatic turnover. The tailored sequence ensures high sensitivity and selectivity in solution. Researchers use it to study renin kinetics, inhibitor potency, and active-site preferences.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: R01025

Custom Peptide Synthesis

cGMP Peptide

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.W/Mr.

2282.7

Sequence

One Letter Code: R-E(EDANS)-IHPFHLVIHT-K(DABCYL)-R
three Letter Code: H-Arg-Glu(EDANS)-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(DABCYL)-Arg-OH (trifluoroacetate salt)

Source#

Synthetic

1. Spatiotemporal delivery of nanoformulated liraglutide for cardiac regeneration after myocardial infarction

2. An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I

3. C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy

4. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes

5. Emu oil in combination with other active ingredients for treating skin imperfections

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Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.

From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.

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