Z-L-asparticacid β-tert.butyl esterN-carboxyanhydride is an aspartic acid-derived N-carboxyanhydride (NCA) in which the amino acid nitrogen is incorporated into the cyclic anhydride, and the side chain corresponds to an aspartate β-carboxyl group masked as a tert-butyl ester while the α-amino functionality is protected as a Z (benzyloxycarbonyl) group. The molecule contains the NCA ring for controlled amide-bond formation, a tert-butyl ester that can be removed under conditions compatible with tert-butyl deprotection, and a carboxylate equivalent that is temporarily esterified to modulate nucleophilicity during polymerization or peptide assembly. As an NCA building block, it is employed to generate aspartate-containing peptide or polypeptide segments in synthetic peptide chemistry, including studies of sequence-defined polymers and preparation of protected aspartate residues for subsequent functionalization or deprotection.
CAT No: CP00441
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