Antazoline Hydrochloride Ph. Eur.
Antazoline Hydrochloride Ph. Eur.
Antazoline hydrochloride is an antagonist of histamine H1 receptors, with anticholinergic properties. It is used to relieve nasal congestion and in eye drops.
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| CAT# | 10-101-108 |
| CAS | 91-75-8 (net), 2508-72-7 (hydrochloride) |
| Synonyms/Alias | 2-(N-Phenyl-N-benzyl-aminomethyl)imidazoline . HCl; 2-[(N-Benzylanilino)methyl]-2-imidazoline . HCl; 4,5-Dihydro-N-phenyl-N-(phenylmethyl)-1H-imidazole-2-methanamine . HCl |
| Chemical Name | N-benzyl-N-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline;hydrochloride |
| M.F/Formula | C17H20ClN3 |
| M.W/Mr. | 265.36 (net), 301.82 (hydrochloride) |
| Sequence | no |
| Labeling Target | Histamine H1 Receptor |
| Application | Conjunctivitis |
| Activity | Antagonist |
| Target | Histamine H1 receptor |
| Short-term Storage Conditions | Dry, dark and at 0 - 4 °C |
Format | neat |
InChI | InChI=1S/C17H19N3.ClH/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16;/h1-10H,11-14H2,(H,18,19);1H |
InChI Key | SWKDMSRRIBZZAY-UHFFFAOYSA-N |
Canonical SMILES | C1CN=C(N1)CN(CC2=CC=CC=C2)C3=CC=CC=C3.Cl |
BoilingPoint | 475.5ºC at 760 mmHg |
Melting Point | 238 °C |
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