Carbidopa (Lodosyn) is a drug given to people with Parkinson's disease in order to inhibit peripheral metabolism oflevodopa. This property is significant in that it allows a greater proportion of peripheral levodopa to cross the blood–brain barrier for central nervous system effect.
CAT# | 10-101-135 |
CAS | 28860-95-9 (net), 38821-49-7 (monohydrate) |
Synonyms/Alias | lodosyn; CARBIDOPA 1-HYDRATE; CARBIDOPA MONOHYDRATE; (S)-3-(3,4-Dihydroxyphenyl)-2- hydrazino-2-methylpropanoic acid · H2O; (S)-α-Hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic acid monohydrate; (-)-L-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinnamic acid monohydrate; α-Methyldopahydrazine monohydrate; MK485, MK 485, MK-485, Carbidopa, Lodosyn |
Chemical Name | (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid |
M.F/Formula | C10H14N2O4 |
M.W/Mr. | 226.23 (net); 244.25 (monohydrate) |
Sequence | One Letter Code: X Three Letter Code: N(NH2)aMeTyr(3-OH)-OH |
Labeling Target | Aromatic-L-amino-acid decarboxylase; Tyrosine-protein kinase Lck; Tyrosine-protein kinase Fyn; Lysine-specific demethylase 4E |
Application | Parkinson's disease |
Appearance | Solid powder |
Purity | >98% (or refer to the Certificate of Analysis) |
Activity | Inhibitor |
Areas of Interest | Cardiovascular System & Diseases Pituitary & Hypothalamic Hormones |
Target | Aromatic-L-amino-acid decarboxylase |
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