Carbidopa (Lodosyn) is a drug given to people with Parkinson's disease in order to inhibit peripheral metabolism oflevodopa. This property is significant in that it allows a greater proportion of peripheral levodopa to cross the blood–brain barrier for central nervous system effect.

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CAS28860-95-9 (net), 38821-49-7 (monohydrate)
Synonyms/Aliaslodosyn; CARBIDOPA 1-HYDRATE; CARBIDOPA MONOHYDRATE; (S)-3-(3,4-Dihydroxyphenyl)-2- hydrazino-2-methylpropanoic acid · H2O; (S)-α-Hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic acid monohydrate; (-)-L-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinnamic acid monohydrate; α-Methyldopahydrazine monohydrate; MK485, MK 485, MK-485, Carbidopa, Lodosyn
Chemical Name(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
M.W/Mr.226.23 (net); 244.25 (monohydrate)
SequenceOne Letter Code: X
Three Letter Code: N(NH2)aMeTyr(3-OH)-OH
Labeling TargetAromatic-L-amino-acid decarboxylase;
Tyrosine-protein kinase Lck;
Tyrosine-protein kinase Fyn;
Lysine-specific demethylase 4E
ApplicationParkinson's disease
AppearanceSolid powder
Purity>98% (or refer to the Certificate of Analysis)
Areas of InterestCardiovascular System & Diseases
Pituitary & Hypothalamic Hormones
TargetAromatic-L-amino-acid decarboxylase
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