Carnosine

Carnosine is a naturally occurring dipeptide composed of beta-alanine and L-histidine, widely utilized in cosmetic formulations for its multifunctional properties. Recognized for its ability to support skin protection against environmental stressors, Carnosine is relevant in anti-aging and skin care applications. Its inclusion in topical products can help maintain overall skin quality, making it suitable for a range of formulations targeting skin vitality and resilience.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Carnosine(CAS 305-84-0)

CAT No: CPC1634

CAS No:305-84-0

Synonyms/Alias:L-Carnosine;Carnosine;305-84-0;beta-Alanyl-L-histidine;Ignotine;Karnozin;Karnozzn;L-Histidine, beta-alanyl-;beta-Alanylhistidine;N-2-M;(2S)-2-(3-aminopropanamido)-3-(1H-imidazol-4-yl)propanoic acid;CHEBI:15727;Nalpha-(beta-alanyl)-L-histidine;L-Ignotine;.beta.-Alanyl-L-histidine;8HO6PVN24W;Polaprezinc;NSC 524045;BRN 0087671;(3-aminopropanoyl)-L-histidine;CARNOSINE [MI];EINECS 206-169-9;CARNOSINE [VANDF];L-HISTIDINE, N-beta-ALANYL-;MFCD00005207;N-beta-alanyl-L-histidine;CARNOSINE [WHO-DD];(2S)-2-(3-aminopropanoylamino)-3-(1H-imidazol-5-yl)propanoic acid;DTXSID80879594;4-25-00-04381 (Beilstein Handbook Reference);N(alpha)-(beta-alanyl)-L-histidine;NSC-524045;(S)-2-(3-Aminopropanamido)-3-(1H-imidazol-5-yl)propanoic acid;L-Histidine, .beta.-alanyl-;Z 103;Z-103;B-Ala-his-oh;(2S)-2-(3-aminopropanamido)-3-(1H-imidazol-5-yl)propanoic acid;L Carnosine;(2~{S})-2-(3-azanylpropanoylamino)-3-(1~{H}-imidazol-4-yl)propanoic acid;beta Alanylhistidine;UNII-8HO6PVN24W;L-Histidine, N-.beta.-alanyl-;DTXSID50861860;Sevitin;LCarnosine;betaAla-His;b-Alanylhistidine;(2S)-2-((3-Amino-1-Oxopropyl)Amino)-3-(3H-Imidazol-4-Yl)Propanoic Acid;(2s)-2-[(3-amino-1-oxopropyl)amino]-3-(3h-imidazol-4-yl)propanoic acid;beta-Ala-His-OH;betaAlanylLhistidine;b-Alanyl-L-histidine;LHistidine, betaalanyl;beta-alanyl-l-histidin;.beta.-Alanylhistidine;LHistidine, Nbetaalanyl;Spectrum_001178;L-Carnosine (Standard);N-b-alanyl-L-Histidine;SpecPlus_000374;CARNOSINE [INCI];Spectrum2_000454;Spectrum3_001212;Spectrum4_001673;Spectrum5_000605;3-aminopropionyl-histidine;bmse000246;bmse001002;C00386;N-(b-Alanyl)-L-histidine;SCHEMBL33769;BSPBio_002624;KBioGR_002225;KBioSS_001658;DivK1c_006470;SPECTRUM1500944;N-(3-Aminopropanoyl)histidine;SPBio_000528;CHEMBL242948;GTPL4559;SCHEMBL25425775;KBio1_001414;KBio2_001658;KBio2_004226;KBio2_006794;KBio3_002124;DTXCID90204277;L-Carnosine, ~99%, crystalline;DTXCID301017603;N-(3-aminopropanoyl)-L-histidine;(2S)-2-(3-aminopropanoylamino)-3-imidazol-4-ylpropanoic acid;HY-W013494R;TNP00340;BDBM50485554;CCG-38696;STL466172;?-Ala-His-OH;?-Alanyl-L-histidine;AKOS010421481;AKOS015963345;CS-W014210;DB11695;FC04033;HY-W013494;SDCCGMLS-0066726.P001;NCGC00017390-01;NCGC00017390-02;NCGC00142487-01;AC-17084;AC-19690;AC-31940;AS-12570;A0222;L-Carnosine, Vetec(TM) reagent grade, 98%;S5226;EN300-302338;H11980;Q413822;SR-05000002473;SR-05000002473-1;(2S)-2-(3-azaniumylpropanoylamino)-3-(1H-imidazol-5-yl)propanoate;(S)-2-(3-aminopropanamido)-3-(1H-imidazol-4-yl)propanoic acid;1370422-07-3;206-169-9;8V0;

Custom Peptide Synthesis
cGMP Peptide
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M.F/Formula
C9H14N4O3
M.W/Mr.
226.23
Sequence
One Letter Code:XH
Three Letter Code:H-bAla-His-OH
Application
Carnosine helps restore skin elasticity and firms the skin, and has good anti-wrinkle and anti-aging effects.
Appearance
White Solid

Mechanism of Action (MOA)

Carnosine is a naturally occurring dipeptide composed of β-alanine and L-histidine. It exhibits antioxidant properties by chelating metal ions and scavenging reactive oxygen species, thereby supporting the maintenance of cellular homeostasis. Additionally, carnosine may modulate cellular signaling pathways related to glycation and oxidative stress, contributing to the stabilization of proteins and cellular structures. These biochemical interactions help maintain the optimal environment for skin cell function.

Carnosine is suitable for incorporation into a variety of cosmetic formulations.

- Facial creams and lotions
- Eye contour products
- Serums and ampoules
- Sheet masks and gel masks
- After-sun care formulations
- Leave-on and rinse-off hair care products

Long-term Storage Conditions
Water (Slightly)
Shipping Condition
Room temperature in continental US; may vary elsewhere.
InChI
InChI=1S/C9H14N4O3/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6/h4-5,7H,1-3,10H2,(H,11,12)(H,13,14)(H,15,16)/t7-/m0/s1
InChI Key
CQOVPNPJLQNMDC-ZETCQYMHSA-N

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