Cyclo[-RGDy-K(5-FAM)]

Name: Cyclo[-RGDy-K(5-FAM)]
Brand: Creative Peptides
Rating: 5 (1 reviews)

This peptide is a 5-FAM-labeled cylic RGDyK peptide. RGD peptides serve as ligands for av-integrin and inhibit angiogenesis, induce endothelial apoptosis, decrease tumor growth, and reduce spread of metastasis.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: X21138

Custom Peptide Synthesis

cGMP Peptide

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.W/Mr.

978

Sequence

One Letter Code: Cyclo[-RGDy-K(5-FAM)]
Three Letter Code: Cyclo[-Arg-Gly-Asp-D-Tyr-Lys(5-FAM)]

References

1. Hausner, S. et a. Cancer Res 67, 7833 (2007);
2. Schottelius, M. et al, Acc Chem Res 42, 969 (2009).

1. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists

2. P-selectin and Complement’s Role in a Neonatal Model of Germinal Matrix Hemorrhage-Induced Secondary Injury

3. High fat diet and GLP-1 drugs induce pancreatic injury in mice

4. An Open-label, Single-center, Safety and Efficacy Study of Eyelash Polygrowth Factor Serum

5. Tachykinin-related peptides modulate immune-gene expression in the mealworm beetle Tenebrio molitor L

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Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.

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