This peptide is a 5-FAM-labeled cylic RGDyK peptide. RGD peptides serve as ligands for av-integrin and inhibit angiogenesis, induce endothelial apoptosis, decrease tumor growth, and reduce spread of metastasis.
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M.W/Mr. | 978 |
Sequence | One Letter Code: Cyclo[-RGDy-K(5-FAM)] Three Letter Code: Cyclo[-Arg-Gly-Asp-D-Tyr-Lys(5-FAM)] |
References | 1. Hausner, S. et a. Cancer Res 67, 7833 (2007); 2. Schottelius, M. et al, Acc Chem Res 42, 969 (2009). |
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