Dalbavancin

Dalbavancin (INN, trade name Dalvance) is a novel second-generation lipoglycopeptide antibiotic. It belongs to the same class as vancomycin.The Food and Drug Administration approved dalbavancin for the treatment of acute bacterial skin and skin structure infections caused by certain susceptible bacteria.

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CAT#10-101-78
CAS171500-79-1
Synonyms/AliasDalbavancin; Zeven; D03640
Chemical Name(2S,3S,4R,5R,6S)-6-[[(1S,2R,19R,22R,34S,37R,40R,52S)-5,32-dichloro-52-[3-(dimethylamino)propylcarbamoyl]-2,26,31,44,49-pentahydroxy-22-(methylamino)-21,35,38,54,56,59-hexaoxo-47-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-7,13,28-trioxa-20,36,39,53,55,58-hexazaundecacyclo[38.14.2.23,6.214,17.219,34.18,12.123,27.129,33.141,45.010,37.046,51]hexahexaconta-3,5,8,10,12(64),14(63),15,17(62),23(61),24,26,29(60),30,32,41(57),42,44,46(51),47,49,65-henicosaen-64-yl]oxy]-3,4-dihydroxy-5-(10-methylundecanoylamino)oxane-2-carboxylic acid
M.F/FormulaC88H100Cl2N10O28
M.W/Mr.1816.69
Labeling TargetBacterial
ApplicationDalbavancin can treat patients infected with methicillin-resistant Staphylococcus aureus (MRSA).
AppearanceOff-white solid powder
Purity>90% (or refer to the Certificate of Analysis)
Biological ActivityDalbavancin (MDL-63397) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria that inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively.
Areas of InterestInfection
DiseaseInfection of skin AND/OR subcutaneous tissue;
Bacterial infection of skin;
Staphylococcal infection of skin
TargetGram-positive bacteria
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