DNA-PK Substrate
A substrate for DNA-dependent protein kinase (DNA-PK), phosphorylation. DNA-PK is essential for the repair of DNA double-strand breaks. This peptide corresponding to 11–24 amino acids of human p53 with threonine 18 and serine 20 changed to alanine is used as a substrate for the assay of DNA-PK activity
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| CAT# | P75006 |
| M.W/Mr. | 1759 |
| Sequence | One Letter Code: EPPLSQEAFADLWKK
Three Letter Code: H-Glu-Pro-Pro-Leu-Ser-Gln-Glu-Ala-Phe-Ala-Asp-Leu-Trp-Lys-Lys-OH |
| Storage | -20°C |
References | 1. Wang, H. et al. Nucleic Acids Res. 31, 5377 (2003);
2. Srivastava, RK. et al. Clinical Cancer Res. 5, 1892 (1999);
3. Suwa, A. et al. J. Clin. Invest. 97, 1417 (1996);
4. Block, W. et al. Nucleic Acids Res. 2, 1967 (2004). |
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