DPDPE is a selective δ-opioid receptor agonist peptide that inhibits electrically stimulated contraction of mouse vas deferens in vitro and is antinociceptive in vivo. DPDPE is a heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond. It has a role as a delta-opioid receptor agonist.
CAT No: R1918
CAS No:88373-73-3
Synonyms/Alias:DPDPE;88373-73-3;(D-Pen2,D-Pen5)-Enkephalin;2,5-Pen-enkephalin;DPLPE;Bis-penicillamine-enkephalin;Enkephalin, D-penicillamine (2,5)-;D-penicillamine-(2,5)-enkephalin;c[D-Pen(2,5)]-enkephalin;(4S,7S,13S)-13-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid;(4s,7s,13s)-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-13-(l-tyrosylamino)-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid;CHEBI:73356;cyclo-[D-Pen(2,5)]-enkephalin;[D-Pen(2)-D-Pen(5)]-enkephaline;H-Tyr-c(D-Pen-Gly-Phe-D-Pen)-OH;Pen(2),pen(5)-enkephalin;CHEMBL31421;H-Tyr-cyclo-(D-Pen-Gly-Phe-D-Pen)-OH;cyclo-[D-Pen2,5]-enkephalin;[D-Pen2-D-Pen5]-enkephaline;Enkephalin, penicillamine(2,5)-;DTXSID201008102;(D-Pen(2),D-pen(5))enkephalin;LY 198572;[3H]DPDPE;D-Valine, L-tyrosyl-3-mercapto-D-valylglycyl-L-phenylalanyl-3-mercapto-, cyclic (2-5)-disulfide;L-tyrosyl-3-mercapto-D-valylglycyl-L-phenylalanyl-3-mercapto-D-valine, cyclic (2-5)-disulfide;(D-Pen2,Pen5)-Enkephalin;c(D-Pen(2,5))-enkephalin;cyclo-(D-Pen2,5)-enkephalin;(D-Pen2-D-Pen5)-enkephaline;cyclo-(D-Pen(2,5))-enkephalin;(D-Pen(2)-D-Pen(5))-enkephaline;Bis-pen-enkephalin;Bis Pen Enkephalin;(4S,7S,13S)-13-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3,3,14,14-tetramethyl-6,9,12-trioxo-7-(phenylmethyl)-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid;Dpdpe(SH)2;D-Pen5-Enkephalin D-Pen2;D Pen2, D Pen5 Enkephalin;D-Pen2, D-Pen5-Enkephalin;D-Pen2, L-Pen5-Enkephalin;D-Penicillamine (2,5)-Enkephalin;(4S,7S,13S)-13-(((2S)-2-amino-3-(4-hydroxyphenyl)propanoyl)amino)-3,3,14,14-tetramethyl-6,9,12-trioxo-7-(phenylmethyl)-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid;Enkephalin, Penicillamine (2,5)-;DPDPE-Cl;DPDPE-OH;[D-Pen2,5]Enkephalin;D-Pen2,D-Pen5]enkephalin;[D-Pen2,D-Pen5]enkephalin;SCHEMBL727022;[D-Pen2, D-Pen5]enkephalin;GTPL1608;BDBM21008;DTXCID501434946;Cyclic [D-Pen2, D-Pen5]enkephalin;Cyclic(D-penicillamine2,5)enkephalin;DB08861;BP108798;DA-63010;H-Tyr-D-Pen(1)-Gly-Phe-D-Pen(1)-OH;NS00071889;C20164;G12225;[2-D-Penicillamine, 5-D-penicillamine]enkephalin;[D-Pen2,5]-Enkephalin hydrate, >=95% (HPLC);Tyr-D-Pen-Gly-Phe-D-Pen [Disulfide Bridge: 2-5];Q27077106;1,2-Dithia-5,8,11-triazacyclotetradecane, cyclic peptide deriv.;Enkephalin, [Tyrosyl-2,6-3H(N)]- (2-D-Penicillamine, 5-D-Penicillamine);L-Tyrosyl-D-penicillamyl-glycyl-L-phenylalanyl-D-penicillamine (2->5)-disulfide;(4S,7S,13S)-13-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid;(4S,7S,13S)-13-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid;1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid, 13-[[(2S)-2-amino-3-(4-hydroxyphenyl)-1-oxopropyl]amino]-3,3,14,14-tetramethyl-6,9,12-trioxo-7-(phenylmethyl)-, (4S,7S,13S)-;D-Valine, L-tyrosyl-3-mercapto-D-valylglycyl-L-phenylalanyl-3- mercapto-, cyclic (2-5)-disulfide;D-Valine, L-tyrosyl-3-mercapto-D-valylglycyl-L-phenylalanyl-3-mercapto-, cyclic (2>5)-disulfide (9CI);D-Valine, L-tyrosyl-3-mercapto-D-valylglycyl-L-phenylalanyl-3-mercapto-, cyclic (2?5)-disulfide;
Chemical Name:(4S,7S,13S)-13-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid
1. Myotropic activity of allatostatins in tenebrionid beetles
3. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists
4. An Open-label, Single-center, Safety and Efficacy Study of Eyelash Polygrowth Factor Serum
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.
Read More