Name: Furin Inhibitor II
Brand: Creative Peptides
SKU: R1834
Availability: MadeToOrder

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Synonyms/Alias	Hexa-D-arginine;673202-67-0;Furin Inhibitor II;D-Argininamide D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-alanine;Furin Inhibitor II trifluoroacetate salt;D-Argininamide, D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-;hexa-D-arginine amide;SCHEMBL19267519;DTXSID90724127;CHEBI:231111;HY-P1028;AKOS024458307;Furin Inhibitor II(Hexa-D-arginine)?;CS-7595;NCGC00505008-01;BS-17319;DA-53444;FF111121;D71119;D-ArgininamideD-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-alanine;H-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2; H-(dR)(dR)(dR)(dR)(dR)(dR)-NH2;(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-amino-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-5-[(diaminomethylidene)amino]pentanamido]-5-[(diaminomethylidene)amino]pentanamido]-5-carbamimidamidopentanamide;(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-amino-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamide;N~5~-(Diaminomethylidene)-D-ornithyl-N~5~-(diaminomethylidene)-D-ornithyl-N~5~-(diaminomethylidene)-D-ornithyl-N~5~-(diaminomethylidene)-D-ornithyl-N~5~-(diaminomethylidene)-D-ornithyl-N~5~-(diaminomethylidene)-D-ornithinamide;
M.F/Formula	C36H75N25O6
M.W/Mr.	954.1
Sequence	One Letter Code:RRRRRR Three Letter Code:H-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2
Purity	98% by HPLC

Source#	Synthetic
Long-term Storage Conditions	H2O : 50 mg/mL (52.40 mM; Need ultrasonic) DMSO : 5 mg/mL (5.24 mM; Need ultrasonic)
Shipping Condition	Shipped at room temperature
InChI	InChI=1S/C36H75N25O6/c37-19(7-1-13-51-31(39)40)26(63)58-21(9-3-15-53-33(43)44)28(65)60-23(11-5-17-55-35(47)48)30(67)61-24(12-6-18-56-36(49)50)29(66)59-22(10-4-16-54-34(45)46)27(64)57-20(25(38)62)8-2-14-52-32(41)42/h19-24H,1-18,37H2,(H2,38,62)(H,57,64)(H,58,63)(H,59,66)(H,60,65)(H,61,67)(H4,39,40,51)(H4,41,42,52)(H4,43,44,53)(H4,45,46,54)(H4,47,48,55)(H4,49,50,56)/t19-,20-,21-,22-,23-,24-/m1/s1
InChI Key	BMLTZEAFQLJTIZ-TZNXUKFXSA-N
Canonical SMILES	C(CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)N)N)CN=C(N)N
Isomeric SMILES	C(C[C@H](C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N)N)CN=C(N)N

1. Zeta-potential-changing nanoparticles conjugated with cell-penetrating peptides for enhanced transfection efficiency

2. High fat diet and GLP-1 drugs induce pancreatic injury in mice

3. Store-operated Ca2+ entry sustains the fertilization Ca2+ signal in pig eggs

4. An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I

5. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function

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Furin Inhibitor II

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