Hexa-D-arginine (Furin Inhibitor II) is a stable furin inhibitor with Ki values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo.
CAT# | R1834 |
CAS | 673202-67-0 |
Synonyms/Alias | Hexa-D-arginine |
M.F/Formula | C36H75N25O6 |
M.W/Mr. | 954.1 |
Sequence | One Letter Code: RRRRRR (Modifications: Arg-6 = C-terminal amide, Arg-1,2,3,4,5,6=D-Arg) Three Letter Code: H-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2 |
Purity | 98% by HPLC |
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