Hexa-D-arginine (Furin Inhibitor II) is a stable furin inhibitor with Ki values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo.
CAT No: R1834
CAS No:673202-67-0
Synonyms/Alias:Hexa-D-arginine;673202-67-0;Furin Inhibitor II;D-Argininamide D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-alanine;Furin Inhibitor II trifluoroacetate salt;D-Argininamide, D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-;hexa-D-arginine amide;SCHEMBL19267519;DTXSID90724127;CHEBI:231111;HY-P1028;AKOS024458307;Furin Inhibitor II(Hexa-D-arginine)?;CS-7595;NCGC00505008-01;BS-17319;DA-53444;FF111121;D71119;D-ArgininamideD-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-alanine;H-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2; H-(dR)(dR)(dR)(dR)(dR)(dR)-NH2;(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-amino-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-5-[(diaminomethylidene)amino]pentanamido]-5-[(diaminomethylidene)amino]pentanamido]-5-carbamimidamidopentanamide;(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-[(2R)-2-amino-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamide;N~5~-(Diaminomethylidene)-D-ornithyl-N~5~-(diaminomethylidene)-D-ornithyl-N~5~-(diaminomethylidene)-D-ornithyl-N~5~-(diaminomethylidene)-D-ornithyl-N~5~-(diaminomethylidene)-D-ornithyl-N~5~-(diaminomethylidene)-D-ornithinamide;
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