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Hygromycin B

Hygromycin B is a fda approved antibiotic food additive for swine and poultry Hygromycin B is an antibiotic produced by the bacterium Streptomyces hygroscopicus. It is an aminoglycoside that kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: Z10-101-165

CAS No:31282-04-9

Synonyms/Alias:Hygromycin b

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cGMP Peptide
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  • CMC information required for an IND
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  • Drug master files (DMF) filing
M.F/Formula
C20H37N3O13
M.W/Mr.
527.52
Labeling Target
30s ribosomal subunit
Application
Hygromycin B, as an antibiotic, used for selection of cells transfected with E. coli hygromycin resistance gene.
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Biological Activity
Hygromycin B is an aminoglycoside antibiotic produced by Streptomyces hygroscopicus. It kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis.
Areas of Interest
Immunology & Inflammation
Cell Biology
Cancer
Functions
Hygromycin B is used as an anthelmintic against swine infections by large roundworms, nodular worms, and whipworms.
Long-term Storage Conditions
Soluble in DMSO
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Short-term Storage Conditions
Dry, dark and at 0 - 4 °C
Solubility
-20 °C
InChI
InChI=1S/C20H37N3O13/c1-23-7-2-5(21)9(26)15(10(7)27)33-19-17-16(11(28)8(4-25)32-19)35-20(36-17)18(31)13(30)12(29)14(34-20)6(22)3-24/h5-19,23-31H,2-4,21-22H2,1H3/t5-,6-,7+,8-,9+,10-,11+,12-,13+,14-,15-,16+,17+,18-,19+,20+/m1/s1
InChI Key
GRRNUXAQVGOGFE-XKIAHZFYSA-N
Isomeric SMILES
CN[C@H]1C[C@H]([C@@H]([C@H]([C@@H]1O)O[C@H]2[C@@H]3[C@H]([C@H]([C@H](O2)CO)O)O[C@]4(O3)[C@@H]([C@H]([C@H]([C@H](O4)[C@@H](CO)N)O)O)O)O)N
BoilingPoint
897.6±65.0 °C at 760 mmHg
ShelfLife
>2 years if stored properly
Melting Point
160-180ºC

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