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Leuprolide Acetate

Leuprolide acetate (Leuprorelin acetate) is a potent gonadotropin-releasing hormone receptor agonist used for the treatment of prostate cancer, endometriosis, uterine fibroids.

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Leuprolide Acetate(CAS 74381-53-6)

CAT No: 10-101-22

CAS No: 74381-53-6

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Synonyms/AliasLeuprolide acetate;Leuprorelin acetate;Lupron;74381-53-6;Carcinil;Lucrin;Eligard;Enantone;Leuplin;Viadur;Lupron Depot;Abbott-43818;Prostap;TAP-144;Fensolvi;Leuprin;Lupaneta;Procrin;Trenantone;Leuplin depot;Lutrate depot;Procren Depot;Uno-Enantone;Depo-Lupron;LUPRON DEPOT-PED;Leuporelin acetate;Lupron PED;TAP-144-SR;Leuprolide Monoacetate;Enanton;Lutrate;Leuprolide acetate depot;LUPRON DEPOT-3;LUPRON DEPOT-4;Abbott 43818;CHEBI:63597;UNII-37JNS02E7V;37JNS02E7V;A-43818;Leuprolide (Acetate);DTXSID7049009;Leuprolide acetate [USAN:USP];DTXCID2028935;Leuprolide acetate [USAN];des-Gly10-[D-Leu6]-LH-RH ethylamide;Leuprolide acetate (USAN:USP);LEUPROLIDE ACETATE (USP-RS);LEUPROLIDE ACETATE [USP-RS];LEUPRORELIN ACETATE (MART.);LEUPRORELIN ACETATE [MART.];MFCD00072080;LEUPRORELIN ACETATE [JAN];LEUPROLIDE ACETATE (USP MONOGRAPH);LEUPROLIDE ACETATE [USP MONOGRAPH];Acetate, Leuprolide;LEUP;MFCD00167544;Ginecrin;Onectyl;Procren;Depo-Eligard;Enantone-Gyn;Fensolvi Kit;Lucrin Depot;Lupron Depot Ped;Leuprolide Acetate?;Lupron Depot-Ped Kit;ELIGARD KIT;Lupron Depot-3 Month;Lupron Depot-4 Month;LUTRATE DEPOT KIT;NCGC00183364-01;SCHEMBL3174;MLS000028695;CHEMBL1200775;LEUPROLIDE ACETATE [VANDF];LEUPROLIDE MONOACETATE [MI];Tox21_113507;BDBM50247891;LEUPRORELIN ACETATE [WHO-DD];s3718;AKOS015895632;AKOS030485977;CCG-270666;CS-1434;FL24877;LEUPROLIDE ACETATE [ORANGE BOOK];5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tryosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide monoacetate (salt);AC-28731;HY-13665;SMR000058945;CAS-74381-53-6;L0249;(Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH acetate;Leuprolide Acetate (53714-56-0 free base);Pyr-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt.HOAc;Q27104908;PGLU-HIS-TRP-SER-TYR-D-LEU-LEU-ARG-PRO-NHC2H5 ACETATE SALT;5-OXO-L-PROLYL-L-HISTIDYL-L-TRYPTOPHYL-L-SERYL-L-TRYOSYL-D-LEUCYL-L-LEUCYL-L-ARGINYL-N-ETHYL-L-PROLINAMIDE ACETATE (SALT);5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tryosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide monoacetate;5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide--acetic acid (1/1);6-D-Leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamideluteinizing hormone-releasing factor acetate;L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-, acetate (1:1);
M.F/FormulaC61H88N16O14
M.W/Mr.1269.4
SequenceOne Letter Code:XHWSYLLRP
Three Letter Code:H-Pyr-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt.CH3CO2H
ActivityAgonist
TargetGonadotropin-releasing hormone receptor
Long-term Storage ConditionsH2O : ≥ 66.66 mg/mL (52.51 mM)
Shipping ConditionRoom temperature in continental US; may vary elsewhere.
InChIInChI=1S/C59H84N16O12.C2H4O2/c1-6-63-57(86)48-14-10-22-75(48)58(87)41(13-9-21-64-59(60)61)68-51(80)42(23-32(2)3)69-52(81)43(24-33(4)5)70-53(82)44(25-34-15-17-37(77)18-16-34)71-56(85)47(30-76)74-54(83)45(26-35-28-65-39-12-8-7-11-38(35)39)72-55(84)46(27-36-29-62-31-66-36)73-50(79)40-19-20-49(78)67-40;1-2(3)4/h7-8,11-12,15-18,28-29,31-33,40-48,65,76-77H,6,9-10,13-14,19-27,30H2,1-5H3,(H,62,66)(H,63,86)(H,67,78)(H,68,80)(H,69,81)(H,70,82)(H,71,85)(H,72,84)(H,73,79)(H,74,83)(H4,60,61,64);1H3,(H,3,4)/t40-,41-,42-,43+,44-,45-,46-,47-,48-;/m0./s1
InChI KeyRGLRXNKKBLIBQS-XNHQSDQCSA-N
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