Leuprolide Acetate

Leuprolide acetate (Leuprorelin acetate) is a potent gonadotropin-releasing hormone receptor agonist used for the treatment of prostate cancer, endometriosis, uterine fibroids.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Leuprolide Acetate(CAS 74381-53-6)

CAT No: 10-101-22

CAS No:74381-53-6

Synonyms/Alias:Leuprolide acetate;Leuprorelin acetate;Lupron;74381-53-6;Carcinil;Lucrin;Eligard;Enantone;Leuplin;Viadur;Lupron Depot;Abbott-43818;Prostap;TAP-144;Fensolvi;Leuprin;Lupaneta;Procrin;Trenantone;Leuplin depot;Lutrate depot;Procren Depot;Uno-Enantone;Depo-Lupron;LUPRON DEPOT-PED;Leuporelin acetate;Lupron PED;TAP-144-SR;Leuprolide Monoacetate;Enanton;Lutrate;Leuprolide acetate depot;LUPRON DEPOT-3;LUPRON DEPOT-4;Abbott 43818;CHEBI:63597;UNII-37JNS02E7V;37JNS02E7V;A-43818;Leuprolide (Acetate);DTXSID7049009;Leuprolide acetate [USAN:USP];DTXCID2028935;Leuprolide acetate [USAN];des-Gly10-[D-Leu6]-LH-RH ethylamide;Leuprolide acetate (USAN:USP);LEUPROLIDE ACETATE (USP-RS);LEUPROLIDE ACETATE [USP-RS];LEUPRORELIN ACETATE (MART.);LEUPRORELIN ACETATE [MART.];MFCD00072080;LEUPRORELIN ACETATE [JAN];LEUPROLIDE ACETATE (USP MONOGRAPH);LEUPROLIDE ACETATE [USP MONOGRAPH];Acetate, Leuprolide;LEUP;MFCD00167544;Ginecrin;Onectyl;Procren;Depo-Eligard;Enantone-Gyn;Fensolvi Kit;Lucrin Depot;Lupron Depot Ped;Leuprolide Acetate?;Lupron Depot-Ped Kit;ELIGARD KIT;Lupron Depot-3 Month;Lupron Depot-4 Month;LUTRATE DEPOT KIT;NCGC00183364-01;SCHEMBL3174;MLS000028695;CHEMBL1200775;LEUPROLIDE ACETATE [VANDF];LEUPROLIDE MONOACETATE [MI];Tox21_113507;BDBM50247891;LEUPRORELIN ACETATE [WHO-DD];s3718;AKOS015895632;AKOS030485977;CCG-270666;CS-1434;FL24877;LEUPROLIDE ACETATE [ORANGE BOOK];5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tryosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide monoacetate (salt);AC-28731;HY-13665;SMR000058945;CAS-74381-53-6;L0249;(Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH acetate;Leuprolide Acetate (53714-56-0 free base);Pyr-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt.HOAc;Q27104908;PGLU-HIS-TRP-SER-TYR-D-LEU-LEU-ARG-PRO-NHC2H5 ACETATE SALT;5-OXO-L-PROLYL-L-HISTIDYL-L-TRYPTOPHYL-L-SERYL-L-TRYOSYL-D-LEUCYL-L-LEUCYL-L-ARGINYL-N-ETHYL-L-PROLINAMIDE ACETATE (SALT);5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tryosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide monoacetate;5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide--acetic acid (1/1);6-D-Leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamideluteinizing hormone-releasing factor acetate;L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-, acetate (1:1);

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C61H88N16O14
M.W/Mr.
1269.4
Sequence
One Letter Code:XHWSYLLRP
Three Letter Code:H-Pyr-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt.CH3CO2H
Activity
Agonist
Target
Gonadotropin-releasing hormone receptor
Long-term Storage Conditions
H2O : ≥ 66.66 mg/mL (52.51 mM)
Shipping Condition
Room temperature in continental US; may vary elsewhere.
InChI
InChI=1S/C59H84N16O12.C2H4O2/c1-6-63-57(86)48-14-10-22-75(48)58(87)41(13-9-21-64-59(60)61)68-51(80)42(23-32(2)3)69-52(81)43(24-33(4)5)70-53(82)44(25-34-15-17-37(77)18-16-34)71-56(85)47(30-76)74-54(83)45(26-35-28-65-39-12-8-7-11-38(35)39)72-55(84)46(27-36-29-62-31-66-36)73-50(79)40-19-20-49(78)67-40;1-2(3)4/h7-8,11-12,15-18,28-29,31-33,40-48,65,76-77H,6,9-10,13-14,19-27,30H2,1-5H3,(H,62,66)(H,63,86)(H,67,78)(H,68,80)(H,69,81)(H,70,82)(H,71,85)(H,72,84)(H,73,79)(H,74,83)(H4,60,61,64);1H3,(H,3,4)/t40-,41-,42-,43+,44-,45-,46-,47-,48-;/m0./s1
InChI Key
RGLRXNKKBLIBQS-XNHQSDQCSA-N

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