Name: MTP-131; RX-31; SS-31 Elamipretide
Brand: Creative Peptides
SKU: R1809
Availability: MadeToOrder

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Synonyms/Alias	Elamipretide;736992-21-5;bendavia;SS-31 peptide;Arg-Dmt-Lys-Phe-NH2;SS31 peptide;MTP-131;D-Arg-Dmt-Lys-Phe-NH2;UNII-87GWG91S09;Ocuvia;Elamipretide [USAN:INN];MTP 131;L-Phenylalaninamide, D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-;Szeto-schiller peptide;SS-31;Nh2-d-arg-dmt-lys-phe-nh2;MTP131;87GWG91S09;RX-31;(2S)-6-amino-2-[[(2S)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]hexanamide;(S)-6-amino-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-((R)-2-amino-5-guanidinopentanamido)-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)hexanamide;Elamipretide [INN];Elamipretida;Elamipretide (USAN/INN);ELAMIPRETIDE [USAN];Elamipretide (MTP-131);ELAMIPRETIDE [WHO-DD];arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide;RX31;SS31;CHEMBL3833370;SCHEMBL15028020;DTXSID50471988;BDBM627985;D-Arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide;D-Arg-Dmt-Lys-Phe-NH2;SS-31;EX-A7058;HY-P0125;MTP-131;MTP 131;MTP131;Bendavia;RX-31;(S)-6-amino-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-((R)-2-amino-5-guanidinopentanamido)-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)hexanamide;s9803;AKOS027326652;CS-5846;DB11981;CVD-0019440;DA-63147;NS00072504;D10925;D78262;Q27269822;
M.F/Formula	C32H49N9O5
M.W/Mr.	639.8
Sequence	One Letter Code:RXKF Three Letter Code:H-D-Arg-Tyr(2,6-diMe)-Lys-Phe-NH2
Activity	Inhibitor
Biological Activity	Elamipretide, also known as MTP-131 or D-Arg-Dmt-Lys-Phe-NH2,is a cardiolipin peroxidase inhibitor and mitochondria-targeted peptide. MTP-131 alleviates mitochondrial dysfunction and oxidative damage in human trabecular meshwork cells. MTP-131 could prevent both iHTM and GTM(3) cells from sustained oxidative stress induced by H(2)O(2).
Target	Cardiolipin Peroxidase

Shipping Condition	Room temperature in continental US; may vary elsewhere.
InChI	InChI=1S/C32H49N9O5/c1-19-15-22(42)16-20(2)23(19)18-27(41-29(44)24(34)11-8-14-38-32(36)37)31(46)39-25(12-6-7-13-33)30(45)40-26(28(35)43)17-21-9-4-3-5-10-21/h3-5,9-10,15-16,24-27,42H,6-8,11-14,17-18,33-34H2,1-2H3,(H2,35,43)(H,39,46)(H,40,45)(H,41,44)(H4,36,37,38)/t24-,25+,26+,27+/m1/s1
InChI Key	SFVLTCAESLKEHH-WKAQUBQDSA-N

1. Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma

2. Identification, Localization in the Central Nervous System and Novel Myostimulatory Effect of Allatostatins in Tenebrio molitor Beetle

3. Myotropic activity and immunolocalization of selected neuropeptides of the burying beetle Nicrophorus vespilloides (Coleoptera: Silphidae)

4. Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment

5. Investigating Potential Interactions Between Neurohypophyseal Peptides, their Drug Analogs, and Coagulation Factor VIII

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MTP-131; RX-31; SS-31 Elamipretide

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