An intravenous infusion of oxytocin is used to induce labor and to support labor in case of slow childbirth.Oxytocin is also used in veterinary medicine to facilitate birth and to stimulate milk release.
CAT No: 10-101-215
CAS No:50-56-6
Synonyms/Alias:OXYTOCIN;50-56-6;Pitocin;Endopituitrina;Ocytocin;Syntocinon;Oxytocinum;Orasthin;Oxitocina;Oxystin;Oxytocine;alpha-Hypophamine;Partocon;Synthetic oxytocin;Piton S;(1-Hemicystine)oxytocin;3-Isoleucine-8-leucine vasopressin;Syntocinone;Ocytocinum;Ossitocina;Oxetakain;Oxoject;Presoxin;Synpitan;Syntocin;Utedrin;Uteracon;Di-sipidin;Nobitocin S;Atonin O;Intertocine S;UNII-1JQS135EYN;HSDB 2182;Oxytocine [INN-French];Oxytocinum [INN-Latin];EINECS 200-048-4;Oxitocina [INN-Spanish];MFCD00076731;BRN 3586108;Vasopressin, 3-L-isoleucine-8-L-leucine-;CHEBI:7872;CHEMBL395429;(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide;OT;DTXSID8048361;OXYTOCIN 5 USP UNITS IN DEXTROSE 5%;Oxytocin [USP:INN:BAN:JAN];OXYTOCIN 10 USP UNITS IN DEXTROSE 5%;OXYTOCIN 20 USP UNITS IN DEXTROSE 5%;TNX1900;TTA-121;TNX-1900;OXT;Oxytocine (INN-French);Oxytocinum (INN-Latin);Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2, cyclic 1-6 disulfide;Oxitocina (INN-Spanish);L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic (1-->6)-disulfide;L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic (1-6)-disulfide;L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic(1-6)-disulfide;Oxytocin (USP:INN:BAN:JAN);[3H]oxytocin;Oxetakain [Czech];1-({(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-leucylglycinamide;Otx;Ossitocina [DCIT];C43H66N12O12S2;[3H]OT (human, mouse, rat);Piton-S;Syntocinon (TN);Oxytocin Injectable;Oxytocin (TN);Oxytocin,(S);(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide;1-(((4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-((1S)-1-methylpropyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl)carbonyl)-L-prolyl-L-leucylglycinamide;Pitocin (TN);CYIQNCPLG;oxytocin, for bioassay;PVL Oxytocin Injectable;(1-Hemicystine)-oxytocin;OXYTOCIN (MART.);OXYTOCIN (USP-RS);1JQS135EYN;SCHEMBL29048;Oxytocin (JP18/USP/INN);GTPL2174;GTPL2176;Oxytocin (High Potency Powder);OXYTOCIN (USP IMPURITY);DTXCID4028335;OXYTOCIN (USP MONOGRAPH);BCBcMAP01_000094;H01BB02;Oxytocin (Label Under Distributors);BDBM50205990;HB2929;TI-001;AKOS015994657;FO35402;HS-2021;NCGC00167132-01;AC-28730;HY-17571;C00746;D00089;SBI-0654087.0001;Q169960;SR-01000945111;SR-01000945111-1;BRD-K25243230-001-01-2;Oxytocin, European Pharmacopoeia (EP) Reference Standard;(Gly-9 = C-terminal amide, disulfide bridge between 1 - 6);Oxytocin, United States Pharmacopeia (USP) Reference Standard;Oxytocin-(leucine-5,5,5-d3, glycine-2,2-d2) trifluoroacetate salt;Oxytocin, lyophilized powder, ~15 IU/mg solid (Prepared from synthetic oxytocin);200-048-4;GLYCINAMIDE, L-CYSTEINYL-L-TYROSYL-L-ISOLEUCYL-L-GLUTAMINYL-L-ASPARAGINYL-L-CYSTEINYL-L-PROLYL-L-LEUCYL-, CYCLIC (1->6)-DISULFIDE;Glycinamide, L-cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-propyl-L-leucyl-, cyclic (1-6)-di-;
Oxytocin Acetate is a synthetic peptide corresponding to the naturally occurring neuropeptide hormone oxytocin, widely recognized for its role in modulating social behavior, neuroendocrine signaling, and smooth muscle contraction. As a nonapeptide, it is structurally characterized by a cyclic backbone formed via a disulfide bridge, conferring both stability and high receptor affinity. In biochemical research, oxytocin and its analogs are pivotal for elucidating mechanisms of peptide hormone signaling, receptor-ligand interactions, and the molecular underpinnings of complex physiological processes. The acetate salt form enhances solubility and handling, making it a practical choice for laboratory experimentation across a range of disciplines, including neurobiology, endocrinology, and pharmacology.
Receptor Binding Studies: Oxytocin Acetate is extensively utilized in receptor binding assays to investigate the specificity, affinity, and kinetics of oxytocin receptor interactions. By employing radiolabeled or fluorescently tagged derivatives, researchers can quantify binding parameters and dissect the structural determinants of receptor activation. These studies are critical for advancing the understanding of G protein-coupled receptor (GPCR) signaling pathways and for screening potential receptor modulators or antagonists in drug discovery pipelines.
Signal Transduction Analysis: The compound serves as a valuable tool for probing intracellular signaling cascades triggered by oxytocin receptor engagement. Experimental systems employing cultured cells or tissue preparations can utilize the peptide to activate downstream pathways such as phospholipase C, calcium mobilization, and MAP kinase signaling. Such analyses provide mechanistic insights into how peptide hormones orchestrate cellular responses, inform the design of pathway-specific probes, and facilitate the identification of novel regulatory proteins involved in neuroendocrine signaling.
Behavioral Neuroscience Research: Oxytocin Acetate is frequently applied in behavioral neuroscience to model the neurochemical basis of social cognition, pair bonding, and stress responsiveness in animal studies. By administering the peptide in controlled experimental settings, researchers can assess its influence on social interaction, anxiety-like behavior, and affiliative processes. These investigations contribute to a deeper understanding of the molecular substrates underlying social behaviors and inform the development of translational models for neuropsychiatric research.
Peptide Structure-Function Studies: The synthetic form of oxytocin enables detailed structure-activity relationship (SAR) analyses, facilitating the exploration of how specific amino acid substitutions or chemical modifications alter biological function. Through systematic analog synthesis and functional testing, investigators can delineate the molecular features required for receptor selectivity and biological efficacy. This approach supports the rational design of novel peptide ligands with tailored pharmacological profiles for both basic and applied research.
Peptide Synthesis and Analytical Method Development: Oxytocin Acetate is also employed as a reference standard and calibration material in peptide synthesis workflows and analytical method validation. Its well-characterized sequence and physicochemical properties make it suitable for optimizing chromatographic separation, mass spectrometric detection, and purity assessment protocols. These applications are essential for establishing robust quality control measures in peptide production and for ensuring the reproducibility of experimental results in both academic and industrial laboratories.
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