An intravenous infusion of oxytocin is used to induce labor and to support labor in case of slow childbirth.Oxytocin is also used in veterinary medicine to facilitate birth and to stimulate milk release.
CAT No: 10-101-215
CAS No:50-56-6
Synonyms/Alias:OXYTOCIN;50-56-6;Pitocin;Endopituitrina;Ocytocin;Syntocinon;Oxytocinum;Orasthin;Oxitocina;Oxystin;Oxytocine;alpha-Hypophamine;Partocon;Synthetic oxytocin;Piton S;(1-Hemicystine)oxytocin;3-Isoleucine-8-leucine vasopressin;Syntocinone;Ocytocinum;Ossitocina;Oxetakain;Oxoject;Presoxin;Synpitan;Syntocin;Utedrin;Uteracon;Di-sipidin;Nobitocin S;Atonin O;Intertocine S;UNII-1JQS135EYN;HSDB 2182;Oxytocine [INN-French];Oxytocinum [INN-Latin];EINECS 200-048-4;Oxitocina [INN-Spanish];MFCD00076731;BRN 3586108;Vasopressin, 3-L-isoleucine-8-L-leucine-;CHEBI:7872;CHEMBL395429;(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide;OT;DTXSID8048361;OXYTOCIN 5 USP UNITS IN DEXTROSE 5%;Oxytocin [USP:INN:BAN:JAN];OXYTOCIN 10 USP UNITS IN DEXTROSE 5%;OXYTOCIN 20 USP UNITS IN DEXTROSE 5%;TNX1900;TTA-121;TNX-1900;OXT;Oxytocine (INN-French);Oxytocinum (INN-Latin);Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2, cyclic 1-6 disulfide;Oxitocina (INN-Spanish);L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic (1-->6)-disulfide;L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic (1-6)-disulfide;L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic(1-6)-disulfide;Oxytocin (USP:INN:BAN:JAN);[3H]oxytocin;Oxetakain [Czech];1-({(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-leucylglycinamide;Otx;Ossitocina [DCIT];C43H66N12O12S2;[3H]OT (human, mouse, rat);Piton-S;Syntocinon (TN);Oxytocin Injectable;Oxytocin (TN);Oxytocin,(S);(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide;1-(((4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-((1S)-1-methylpropyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl)carbonyl)-L-prolyl-L-leucylglycinamide;Pitocin (TN);CYIQNCPLG;oxytocin, for bioassay;PVL Oxytocin Injectable;(1-Hemicystine)-oxytocin;OXYTOCIN (MART.);OXYTOCIN (USP-RS);1JQS135EYN;SCHEMBL29048;Oxytocin (JP18/USP/INN);GTPL2174;GTPL2176;Oxytocin (High Potency Powder);OXYTOCIN (USP IMPURITY);DTXCID4028335;OXYTOCIN (USP MONOGRAPH);BCBcMAP01_000094;H01BB02;Oxytocin (Label Under Distributors);BDBM50205990;HB2929;TI-001;AKOS015994657;FO35402;HS-2021;NCGC00167132-01;AC-28730;HY-17571;C00746;D00089;SBI-0654087.0001;Q169960;SR-01000945111;SR-01000945111-1;BRD-K25243230-001-01-2;Oxytocin, European Pharmacopoeia (EP) Reference Standard;(Gly-9 = C-terminal amide, disulfide bridge between 1 - 6);Oxytocin, United States Pharmacopeia (USP) Reference Standard;Oxytocin-(leucine-5,5,5-d3, glycine-2,2-d2) trifluoroacetate salt;Oxytocin, lyophilized powder, ~15 IU/mg solid (Prepared from synthetic oxytocin);200-048-4;GLYCINAMIDE, L-CYSTEINYL-L-TYROSYL-L-ISOLEUCYL-L-GLUTAMINYL-L-ASPARAGINYL-L-CYSTEINYL-L-PROLYL-L-LEUCYL-, CYCLIC (1->6)-DISULFIDE;Glycinamide, L-cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-propyl-L-leucyl-, cyclic (1-6)-di-;
Oxytocin Acetate is a synthetic peptide analog of the naturally occurring neuropeptide oxytocin, widely recognized for its diverse roles in physiological and behavioral processes across various species. This compound is characterized by its nonapeptide structure and acetylated form, which enhances its stability and suitability for laboratory applications. Researchers value Oxytocin Acetate for its ability to mimic endogenous oxytocin activity, making it a fundamental tool for investigating intricate signaling pathways and receptor interactions. Its high solubility and compatibility with aqueous solutions further facilitate its integration into a range of experimental protocols, enabling precise control over dosing and administration. As a result, Oxytocin Acetate has become indispensable in advancing our understanding of neuroendocrine regulation, social behaviors, and cellular communication.
Neurobiology Research: In the field of neurobiology, Oxytocin Acetate is extensively utilized to dissect the molecular and cellular mechanisms underlying social bonding, stress responses, and emotional regulation. By applying this peptide to in vitro or in vivo models, scientists can observe its effects on neuronal activity, synaptic plasticity, and neurotransmitter release. These studies have illuminated the role of oxytocinergic signaling in modulating anxiety, trust, and affiliative behaviors, contributing to the broader comprehension of social cognition and neuropsychiatric disorders. The use of Oxytocin Acetate in these experimental paradigms allows for the identification of downstream signaling cascades and potential molecular targets for future intervention research.
Endocrine System Studies: Oxytocin Acetate serves as a valuable reagent in the exploration of hormone regulation within the endocrine system. Researchers employ it to stimulate or inhibit specific pathways involved in reproductive physiology, lactation, and parturition in animal models. By monitoring the hormonal feedback loops and receptor expression patterns elicited by this peptide, investigators gain insights into the dynamic interplay between the hypothalamus, pituitary gland, and peripheral tissues. These findings not only deepen the understanding of endocrine homeostasis but also provide foundational knowledge for the development of new research models in reproductive biology and neuroendocrinology.
Behavioral Science Investigations: The study of social and affiliative behaviors benefits significantly from the application of Oxytocin Acetate in controlled laboratory settings. Behavioral scientists administer this compound to assess its influence on pair bonding, maternal care, and group interactions among various animal species. Through carefully designed experiments, it becomes possible to delineate the neural circuits and genetic factors that govern complex social behaviors. The reproducibility and specificity of Oxytocin Acetate make it an ideal agent for elucidating the biological substrates that underlie empathy, cooperation, and social recognition.
Pharmacological Screening: In pharmacological research, Oxytocin Acetate is frequently used as a reference compound for screening novel ligands and modulators of the oxytocin receptor. High-throughput assays and binding studies leverage its well-characterized activity profile to benchmark the efficacy and selectivity of new molecular entities. This approach accelerates the identification of candidates with potential to modulate oxytocinergic signaling for basic science applications. Furthermore, the comparative data generated through these screenings contribute to the refinement of structure-activity relationships and the optimization of experimental models.
Cell Signaling Pathway Analysis: The investigation of intracellular signaling pathways benefits from the precise application of Oxytocin Acetate in cell culture and tissue preparations. By stimulating oxytocin receptors on target cells, researchers can monitor downstream events such as calcium mobilization, MAPK activation, and gene transcription. These mechanistic studies provide a detailed understanding of how oxytocinergic signals are transduced within diverse cell types, including neurons, myocytes, and epithelial cells. The insights gained from such analyses are instrumental in mapping the cellular networks that coordinate physiological responses to environmental and internal cues.
In summary, Oxytocin Acetate stands as a versatile and essential tool for researchers across multiple disciplines, including neurobiology, endocrinology, behavioral science, pharmacology, and cell biology. Its application in experimental models continues to yield critical insights into the molecular, cellular, and behavioral dimensions of oxytocin signaling. As scientific exploration advances, the strategic use of this peptide compound will remain pivotal in unraveling the complexities of neuroendocrine communication and social behavior, ultimately driving progress in fundamental and translational research.
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5. Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment
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