Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor®, which is used in the treatment of Cushing's disease.

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Synonyms/AliasSOM 230;Pasireotidum
SequenceOne Letter Code: cyclo((4R)-4-(2-Aminoethylcarbamoyloxy)-LPFWK-4-O-benzyl-YF-)
Three Letter Code: cyclo((4R)-4-(2-Aminoethylcarbamoyloxy)-L-Pro-L-Phe-D-Trp-L-Lys-4-O-benzyl-L-Tyr-L- Phe-)
ApplicationPasireotide is used for the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery has not been curative or is not an option.
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