Name: Protirelin
Brand: Creative Peptides
SKU: 10-101-51
Availability: MadeToOrder

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Synonyms/Alias	protirelin;24305-27-9;Thyroliberin;Lopremone;Synthetic TRH;Rifathyroin;Thypinone;Thyrotropin-releasing factor;TSH-releasing factor;Protirelina;Protireline;Thyrotropic-releasing factor;5-Oxo-L-prolyl-L-histidyl-L-prolinamide;Protirelinum;THYREL TRH;Relefact TRH;TRH;Abbott 38579;ABBOTT-38579;Protirelin, synthetic;Synthetic tsh-releasing factor;L-Pyroglutamyl-L-histidyl-L-prolinamide;5-oxo-pro-his-pro-nh2;L-Pyroglutamyl-L-histidyl-L-prolineamide;Protireline [INN-French];Protirelinum [INN-Latin];FDA 1725;L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-;Protirelina [INN-Spanish];CCRIS 2593;117217-40-0;Ro 8-6270/9;CHEBI:35940;Relefact TRH (TN);HOLO-TRANSFERRIN;Protirelin [USAN:INN:BAN:JAN];Protirelin tartrate;PROTIRELIN [INN];PROTIRELIN [JAN];EINECS 246-143-4;PROTIRELIN [USAN];(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide;PROTIRELIN [VANDF];5Y5F15120W;NSC-760113;PROTIRELIN [MART.];PROTIRELIN [WHO-DD];L-Pyroglutamyl-L-histidinyl-L-prolinamide;DTXCID403533;DTXSID0023533;PROTIRELIN [ORANGE BOOK];PROTIRELIN [EP MONOGRAPH];24305-27-9 (free base);A-38579;NSC 760113;NCGC00160616-01;Protireline (INN-French);Protirelinum (INN-Latin);Protirelina (INN-Spanish);PROTIRELIN (MART.);(S)-N-((S)-1-((S)-2-carbamoylpyrrolidin-1-yl)-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl)-5-oxopyrrolidine-2-carboxamide;PROTIRELIN (EP MONOGRAPH);(2S)-N-[(2S)-1-[(2S)-2-aminocarbonylpyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxidanylidene-propan-2-yl]-5-oxidanylidene-pyrrolidine-2-carboxamide;pyroglutamyl-histidyl-prolylamide;Thyrefact;Trh-cambridge;Protirelin?;trh-sr;Synthetic TRF;UNII-5Y5F15120W;Human Transferrin;Relefact-TRH;TRH, Relefact;Stimu-TSH;Thyrotropin-releasing factor (pig);(2S)-N-((2S)-1-((2S)-2-aminocarbonylpyrrolidin-1-yl)-3-(1H-imidazol-5-yl)-1-oxidanylidene-propan-2-yl)-5-oxidanylidene-pyrrolidine-2-carboxamide;(2S)-N-((2S)-1-((2S)-2-carbamoylpyrrolidin-1-yl)-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl)-5-oxopyrrolidine-2-carboxamide;PR 546;PR-546;Synthetic thyrotropin-releasing factor;Pyr-His-Pro-NH2;Abbott38579;PyroGlu-His-prolinamide;Thyroliberin TRH Merck;TSH-RF;TRH [MI];Thyrotropin Releasing Factor;CHEMBL1472;SCHEMBL33419;[3H]-TRH;GTPL2139;GTPL3836;Siderophilin;partially saturated;pyroglutamyl-histidyl-prolinamide;Protirelin (JP18/USAN/INN);SCHEMBL19825647;[3H]TRH (human, mouse, rat);V04CJ02;Thyrotropin Releasing Hormone TRH;BCP12450;HY-P0002;Synthetic thyrotopin releasing factor;Tox21_111939;BDBM50072394;s4680;AKOS015994636;AKOS040759052;CCG-268193;DB09421;FP33965;HS-2023;Protirelin;Thyrotropin-Releasing Hormone;(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(3H-imidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide;DA-64226;L-Pyroglutamyl-L-histidyl-L-proline amide;CAS-24305-27-9;NS00006015;C03958;C74244;D00176;Prolinamide, 5-oxo-L-prolyl-L-histidyl-, L-;L-PYROGLUTAMYL-L-HISTIDYL-L-PROLINE-AMIDE;(Pyro)-L-glutamic acid-L-histidine-L-proline-NH2;A858244;EN300-27034140;Q24726011;Prolinamide, 1-[N-(5-oxo-L-prolyl)-L-histidyl]-, L-;pyroGlu-His-Pro-NH2 (or 5-oxo-L-prolyl-L-histidyl-L-prolinamide);(2S)-1-[(2S)-3-(1H-IMIDAZOL-4-YL)-2-{[(2S)-5-OXOPYRROLIDIN-2-YL]FORMAMIDO}PROPANOYL]PYRROLIDINE-2-CARBOXAMIDE;(2S)-1-[(2S)-3-(1H-imidazol-5-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanoyl]pyrrolidine-2-carboxamide;(2S)-1-[(2S)-3-(imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanoyl]pyrrolidine-2-carboxamide;(2S)-N-[(1S)-2-[(2S)-2-carbamoylpyrrolidino]-1-(1H-imidazol-5-ylmethyl)-2-keto-ethyl]-5-keto-pyrrolidine-2-carboxamide;1-(3-(1H-Imidazol-5-yl)-2-([(5-oxo-2-pyrrolidinyl)carbonyl]amino)propanoyl)-2-pyrrolidinecarboxamide #;1-[3-(1H-4-imidazolyl)-2-(5-oxotetrahydro-1H-2-pyrrolylcarboxamido)propanoyl]tetrahydro-1H-2-pyrrolecarboxamide;2-Pyrrolidinecarboxamide, N-[1-[(2-carbamoyl-1-pyrrolidinyl)carbonyl]-2-imidazol-4-ylethyl]-5-oxo-,;2-Pyrrolidinecarboxamide, N-[1-[(2-Carbamoyl-1-pyrrolidinyl)carbonyl]-2-imidazol-4-ylethyl]-5-oxo-, (S,S,S)-;246-143-4;
M.F/Formula	C16H22N6O4
M.W/Mr.	362.38
Sequence	One Letter Code:XHP Three Letter Code:H-Pyr-His-Pro-NH2
Application	TRH has been used clinically for the treatment of spinocerebellar degeneration and disturbance of consciousness in humans.
Appearance	Solid powder
Target	Thyroid Hormone Receptor

Shipping Condition	Room temperature in continental US; may vary elsewhere.
InChI	InChI=1S/C16H22N6O4/c17-14(24)12-2-1-5-22(12)16(26)11(6-9-7-18-8-19-9)21-15(25)10-3-4-13(23)20-10/h7-8,10-12H,1-6H2,(H2,17,24)(H,18,19)(H,20,23)(H,21,25)/t10-,11-,12-/m0/s1
InChI Key	XNSAINXGIQZQOO-SRVKXCTJSA-N

1. Myotropic activity and immunolocalization of selected neuropeptides of the burying beetle Nicrophorus vespilloides (Coleoptera: Silphidae)

2. High fat diet and GLP-1 drugs induce pancreatic injury in mice

3. Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment

4. Cationic cell-penetrating peptides are potent furin inhibitors

5. Uncarboxylated osteocalcin decreases insulin-stimulated glucose uptake without affecting insulin signaling and regulators of mitochondrial biogenesis in myotubes

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