Secretin (porcine) Hydrochloride

Tetracosactide is a synthetic peptide, which corresponds to the first 24 amino acids of the naturally occurring hormone ACTH (adrenocorticotropic hormone). It stimulates the adrenal cortex to produce corticosteroids, mineralocorticoids, and, to a lesser extent, androgens.

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ExplanationSecretin stimulates the secretion of bicarbonate by the pancreas and inhibits the gastrin and acid production in the stomach. It also potentiates the release of digestive enzymes from the pancreas triggered by cholecystokinin.
Synonyms/AliasRG 1068; RG1068; RG-1069; Secretin
SequenceH-His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Asp-Ser-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2 hydrochloride salt
Labeling TargetSecretin receptor
ApplicationSecretin has been widely used in medical field especially in pancreatic functioning test, since it promotes the normal growth and maintenance of the pancreas. Secretin also plays a role in the regulation of body water homeostasis and food intake.
Areas of InterestGastrointestinal Research
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