δ-Sleep Inducing Peptide

δ-Sleep Inducing Peptide is a neuropeptide, with antioxidant and anxiolytic properties.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
δ-Sleep Inducing Peptide(CAS 62568-57-4)

CAT No: R1802

CAS No:62568-57-4

Synonyms/Alias:Emideltide;62568-57-4;DELTA SLEEP INDUCING PEPTIDE;DSIP;DSIP nonapeptide;Emideltide [INN];DELTA SLEEP-INDUCING PEPTIDE;emideltida;TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU;UNII-YN28Z5YZ73;Delta sleep-inducing peptide (rabbit);YN28Z5YZ73;L-Glutamic acid, L-tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-;69431-45-4;L-Glutamic acid, N-(N-(N-(N-(N-(N-(N-(N-L-tryptophyl-L-alanyl)glycyl)glycyl)-L-alpha-aspartyl)-L-alanyl)-L-seryl)-glycyl)-;L-Tryptophyl-L-alanylglycylglycyl-L-alpha-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid;Delta Sleep Peptide;Delta Sleep-Inducing Peptide (DSIP);Delta Sleep-Inducing Peptide [DSIP];L-tryptophyl-L-alanylglycylglycyl-L-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid;Delta-Sleep Inducing Peptide;Delta-Sleep Peptide;Peptide, Delta-Sleep;emideltidum;Delta-Sleep-Inducing Peptide;Delta-Sleep-Inducing-Peptide;Peptide, Delta Sleep-Inducing;Peptide, Delta-Sleep-Inducing;Sleep-Inducing Peptide, Delta;Trp Ala Gly Gly Asp Ala Ser Gly Glu;DSIP?;??-Sleep Inducing Peptide;Delta-Sleep Inducing Peptide trifluoroacetate salt;SCHEMBL5523017;CHEMBL2104403;DTXSID20978151;GLXC-25919;PDS-4054-V;EX-A8102;HY-P1501;PDS-4054;AKOS040759081;FD108702;DB-230598;CS-0044577;NS00127321;Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu * 4H2O;Q27294600;H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH; H-WAGGDASGE-OH;L-tryptophyl-L-alanyl-glycyl-glycyl-L-alpha-aspartyl-L-alanyl-L-seryl-glycyl-L-glutamic acid;(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]acetyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]pentanedioic acid;(3S,9S,12S,15S)-15-(2-(2-((S)-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)propanamido)acetamido)acetamido)-9-(hydroxymethyl)-12-methyl-5,8,11,14-tetraoxo-4,7,10,13-tetraazahexadecane-1,3,16-tricarboxylic acid;N-[23-Amino-11-(carboxymethyl)-1,4,7,10,13,16,19,22-octahydroxy-5-(hydroxymethyl)-24-(1H-indol-3-yl)-8,20-dimethyl-3,6,9,12,15,18,21-heptaazatetracosa-3,6,9,12,15,18,21-heptaen-1-ylidene]glutamic acid;

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cGMP Peptide
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M.F/Formula
C35H48N10O15
M.W/Mr.
848.8
Sequence
One Letter Code:WAGGDASGE
Three Letter Code:H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH

δ-Sleep Inducing Peptide is a synthetic peptide compound recognized for its role as a neuropeptide and its significance in neurobiological research. Characterized by its distinct amino acid sequence, this compound has been extensively studied for its involvement in sleep regulation and central nervous system signaling. Its unique structure and biological activity make it a valuable tool for probing peptide-mediated pathways within the brain, particularly those associated with sleep, circadian rhythms, and neurochemical modulation. As a research-use peptide, δ-Sleep Inducing Peptide provides scientists with a means to dissect the molecular mechanisms underlying neuropeptide function and to explore the broader landscape of peptide signaling in neurobiological systems.

Neuroscience research: δ-Sleep Inducing Peptide is widely utilized in neuroscience laboratories to investigate the molecular and cellular mechanisms governing sleep and wakefulness. By administering this peptide in experimental models, researchers can assess its effects on neuronal activity, neurotransmitter release, and sleep architecture. Such studies help clarify the neurochemical pathways involved in sleep regulation and provide a foundation for understanding how endogenous peptides modulate brain function in physiological and experimental contexts.

Peptide receptor studies: The compound serves as an essential probe for characterizing peptide receptor interactions in the central nervous system. Its ability to selectively interact with specific neuropeptide receptors enables researchers to delineate receptor subtypes, binding affinities, and downstream signaling cascades. These investigations are crucial for mapping the complex network of peptide-mediated communication in neural tissues and for identifying molecular targets relevant to neuropeptide signaling.

Signal transduction analysis: δ-Sleep Inducing Peptide is employed in research focused on intracellular signaling pathways activated by neuropeptides. By examining changes in second messenger systems, phosphorylation events, and gene expression following exposure to this peptide, scientists gain insights into the transduction mechanisms that translate extracellular peptide signals into cellular responses. Such analyses contribute to a deeper understanding of how neuropeptides orchestrate diverse physiological processes at the molecular level.

Peptide structure-activity relationship (SAR) studies: The defined sequence and bioactivity of δ-Sleep Inducing Peptide make it an excellent subject for structure-activity relationship investigations. Researchers can utilize the peptide as a reference compound to evaluate the impact of sequence modifications, analog design, or chemical modifications on biological activity. These SAR studies inform the rational design of novel peptide analogs with tailored properties for advanced neurobiological research.

Analytical method development: The compound is also valuable in the development and validation of analytical techniques for peptide detection and quantification. Its well-characterized properties allow it to serve as a model analyte in mass spectrometry, high-performance liquid chromatography, and immunoassay protocols. Such applications facilitate the optimization of analytical workflows for neuropeptide measurement in complex biological samples, enhancing the precision and reliability of peptide quantification in research settings.

Source#
Synthetic
Long-term Storage Conditions
Soluble in water at 0.5mg/ml
Shipping Condition
Room temperature in continental US; may vary elsewhere.
InChI
InChI=1S/C35H48N10O15/c1-16(41-32(56)20(36)9-18-11-37-21-6-4-3-5-19(18)21)30(54)39-12-25(47)38-13-26(48)44-23(10-29(52)53)34(58)42-17(2)31(55)45-24(15-46)33(57)40-14-27(49)43-22(35(59)60)7-8-28(50)51/h3-6,11,16-17,20,22-24,37,46H,7-10,12-15,36H2,1-2H3,(H,38,47)(H,39,54)(H,40,57)(H,41,56)(H,42,58)(H,43,49)(H,44,48)(H,45,55)(H,50,51)(H,52,53)(H,59,60)/t16-,17-,20-,22-,23-,24-/m0/s1
InChI Key
ZRZROXNBKJAOKB-GFVHOAGBSA-N

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