Somatostatin Acetate

Somatostatin is a tetradecapeptide which can suppress the growth hormone (GH) secretion and control the pituitary hormone secretion in human CNS.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: 10-101-32

CAS No:38916-34-6 (net), 51110-01-1 (acetate)

Synonyms/Alias:SOMATOSTATIN;38916-34-6;Cyclic Somatostatin;Somatostatina;Somatostatine;Somatostatin-14;Somatostatinum;Somatostatin, cyclic;Somatostatin (sheep);Somatostatin 14;Somatostatin acetate;Synthetic somatostatin-14;Somatostatin (rat);Aminopan;Somatostatine [INN-French];Somatostatinum [INN-Latin];Somatostatin (human);Somatostatina [INN-Spanish];Somatostatin (pigeon);CCRIS 3629;Somatostatin [INN:BAN];EINECS 254-186-5;Stilamin;SRIF 14;UNII-6E20216Q0L;MFCD00076762;SOMATOSTATIN [MI];SOMATOSTATIN [INN];SR 9357;SOMATOSTATIN [MART.];Somiaton;SOMATOSTATIN [WHO-DD];CHEBI:64628;SOMATOSTATIN [EP MONOGRAPH];Somatostatin (INN);SRIF;6E20216Q0L;Somatotropin release-inhibiting factor;Somatostatine (INN-French);Somatostatinum (INN-Latin);Somatostatina (INN-Spanish);SOMATOSTATIN (MART.);15-28-Somatostatin-28;CCRIS 7071;SOMATOSTATIN (EP MONOGRAPH);EINECS 256-969-7;Ala-Gly-cyclo-[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys];L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide;L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine cyclic (3-14) disulfide;DTXCID6026793;SRIH-14;Ala-Gly-cyclo-(Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys);Somatostatin-1;L-alanyl-N-((4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis((1R)-1-hydroxyethyl)-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl)glycinamide;Somatotropin release inhibiting factor;Recombinant Somatostatin;GH-RIH;Somatostatin-14 Acetate;CHEMBL1823872;SCHEMBL21361053;BDBM81767;H01CB01;AKOS015994634;AC-8931;DB09099;FS27855;HS-2027;NCGC00167137-01;CAS_38916-34-6;CB6417646;C74981;BRD-K14681867-001-01-6;BRD-K14681867-015-01-6;Q22075835;Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH(Cys3-Cys14);ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH,CYS-CYS;ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS 3,14-disulfide;254-186-5;256-969-7;Somatostatin-14 (H-L-Ala-L-Gly-L-Cys(1)-L-Lys-L-Asn-L-Phe-L-Phe-L-Trp-L-Lys-L-Thr-L-Phe-L-Thr-L-Ser-L-Cys(1)-OH);

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C76H104N18O19S2
M.W/Mr.
1637.9
Sequence
One Letter Code:AGCKNFFWKTFTSC
Three Letter Code:H-Ala-Gly-Cys(1)-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys(1)-OH
Application
Somatostatin acetate is used in the treatment of severe, acute hemorrhages of gastroduodenal ulcers. It is also an experimental anti-diabetic agent.
Shipping Condition
Room temperature in continental US; may vary elsewhere.
InChI
InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1
InChI Key
NHXLMOGPVYXJNR-ATOGVRKGSA-N

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