Ziconotide

Name: Ziconotide
Brand: Creative Peptides
SKU: 10-101-62
Availability: MadeToOrder

Ziconotide is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects.

Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).

CAT No: 10-101-62

CAS No: 107452-89-1

Synonyms/Alias: Ziconotide;Prialt;omega-conotoxin MVIIA;SNX-111;107452-89-1;omega-Conotoxin M VIIA;Ziconotida;omega-Conopeptide MVIIA (Conus);DRG-0250;UNII-7I64C51O16;HSDB 7609;MFCD00145036;150770-63-1;DTXSID60883174;omega-Conotoxin M VIIA (reduced), cyclic (1-16),(8-20),(15-25)-tris(disulfide);7I64C51O16;H-Cys-Lys-Gly-Lys-Gly-Ala-Lys-Cys-Ser-Arg-Leu-Met-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cy;omega-Conotoxin mviia, conus magus;Ziconotide [USAN:INN];ziconotidum;o-Conotoxin MVIIA;.omega.-conotoxin m viia;ZICONOTIDE (MART.);GTPL2536;CHEMBL4594214;N02BG08;CHEBI:135912;CHEBI:142406;DTXCID901323852;HY-P0062;AKOS015994641;AC-8938;AT42420;HS-2032;FC110295;omega-Conotoxin MVIIA, >=95% (HPLC);CS-0015087;NS00068028;?-Conotoxin M VIIA Acetate; ?-Conopeptide MVIIA Acetate; Prialt Acetate; SNX 111;;L-Cysteinyl-L-lysylglycyl-L-lysylglycyl-L-alanyl-L-lysyl-L-cysteinyl-L-seryl-L-arginyl-L-leucyl-L-methionyl-L-tyrosyl-L-alpha-aspartyl-L-cysteinyl-L-cysteinyl-L-threonylglycyl-L-seryl-L-cysteinyl-L-arginyl-L-serylglycyl-L-lysyl-L-cysteinamide cyclic (1-16),(8-20),(15-25)-tris(disulfide);

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Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C102H172N36O32S7
M.W/Mr.	2639.2
Sequence	One Letter Code:CKGKGAKCSRLMYDCCTGSCRSGKC Three Letter Code:H-Cys(1)-Lys-Gly-Lys-Gly-Ala-Lys-Cys(2)-Ser-Arg-Leu-Met-Tyr-Asp-Cys(3)-Cys(1)-Thr-Gly-Ser-Cys(2)-Arg-Ser-Gly-Lys-Cys(3)-NH2
Appearance	Ziconotide (SNX-111), a peptide, is a potent and selective block of N-type calcium channels antagonist. Ziconotide reduces synaptic transmission, and can be used for chronic pain research.
Activity	Antagonist
Target	Calcium Channel

Shipping Condition	Room temperature in continental US; may vary elsewhere.
InChI	InChI=1S/C102H172N36O32S7/c1-50(2)34-63-91(161)127-62(26-33-171-5)90(160)129-64(35-53-22-24-54(143)25-23-53)92(162)130-65(36-78(148)149)93(163)135-72-48-175-173-45-69(80(108)150)133-86(156)58(18-8-12-29-105)121-76(146)39-117-85(155)66(41-139)131-88(158)61(21-15-32-114-102(111)112)126-96(166)70-46-176-177-47-71(97(167)132-68(43-141)95(165)125-60(87(157)128-63)20-14-31-113-101(109)110)134-89(159)59(19-9-13-30-106)123-81(151)51(3)119-74(144)37-115-83(153)56(16-6-10-27-103)120-75(145)38-116-84(154)57(17-7-11-28-104)124-82(152)55(107)44-172-174-49-73(137-98(72)168)99(169)138-79(52(4)142)100(170)118-40-77(147)122-67(42-140)94(164)136-70/h22-25,50-52,55-73,79,139-143H,6-21,26-49,103-107H2,1-5H3,(H2,108,150)(H,115,153)(H,116,154)(H,117,155)(H,118,170)(H,119,144)(H,120,145)(H,121,146)(H,122,147)(H,123,151)(H,124,152)(H,125,165)(H,126,166)(H,127,161)(H,128,157)(H,129,160)(H,130,162)(H,131,158)(H,132,167)(H,133,156)(H,134,159)(H,135,163)(H,136,164)(H,137,168)(H,138,169)(H,148,149)(H4,109,110,113)(H4,111,112,114)/t51-,52+,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,79-/m0/s1
InChI Key	BPKIMPVREBSLAJ-QTBYCLKRSA-N

1. Effect of Short-Term Desiccation, Recovery Time, and CAPA-PVK Neuropeptide on the Immune System of the Burying Beetle Nicrophorus vespilloides

2. Emerging applications of nanotechnology for diagnosis and therapy of disease: a review

3. Myotropic activity and immunolocalization of selected neuropeptides of the burying beetle Nicrophorus vespilloides (Coleoptera: Silphidae)

4. Peptides as Active Ingredients: A Challenge for Cosmeceutical Industry

5. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes

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